Genetic Testing for Hereditary Breast/Ovarian Cancer(BRCA1/2)

• 

According to research reports, individuals with inherited cancer genes have a higher risk of cancer than ordinary people. About 7% of breast cancer and 1%-15% of ovarian cancer are caused by brca1 and brca2 genesmutations. In families with a high incidence of breast and ovarian cancer, 80% of patients have mutations in the BRCA1/BRCA2 gene, and this gene is inherited in an autosomal dominant manner in the population.

This test detects the entire coding region of BRCA1/BRCA2 genes, and 20bp intron regions upstream and downstream of the coding region, in addition to known mutation hotspot genes, unknown mutations can be detected.

Clinical applications:

Preventive guidance - Detection of brca1 and brca2 testinggene mutations can provide references for disease risk assessment to high-risk groups or healthy people, reduce the risk of disease through preventive treatment, and provide references for disease risk assessment to relatives of mutation carriers.

Medication guidance - Breast cancer and ovarian cancer patients with BRCA1/BRCA2 mutations are more sensitive to platinum and PARP inhibitor drugs (Olaparib), A large proportion of patients with BRCA1/ BRCA2 gene mutations are triple-negative breast cancers, which are more sensitive to platinum-based chemotherapy.

Prognostic assessment - BRCA1/BRCA2 gene mutation carriers have a relatively high risk of ipsilateral breast recurrence or contralateral breast cancer. BRCA1/BRCA2 gene mutations are relative contraindication to breast-conserving therapy.

For more information about breast cancer brcaand in vitro diagnostics, please feel free to contact us!

There are many rna sequencing companies, but we are one of the best choices for you.

Другие товары поставщика

	Genetic Testing for Blood Cancer	This test can detect SNV, Indel, and FLT3-ITD information of 232 genes associated with blood cancers, covers all types of leukemia - AML/ALL/CML/CL...
	Individualized Medication Guidance for Prostate Cancer	This test detects 346 genes, including HRR pathway genes. The content involves targeted therapy, immunotherapy, chemotherapy and hereditary risk as...
	CapitalBio® DNA Microarray Scanner LuxScan™10K	CapitalBio® DNA Microarray Scanner LuxScan™10K The CapitalBio LuxScan™ 10K microarray gene array scanner is a compact high perform...
	Forensic Platform	Forensic DNA identification is a scientific and technological weapon for investigation and litigation. The inspection includes DNA extraction, PCR ...
	Folic Acid Utilization Ability Genetic Detection	Folic acid is mainly involved in nucleic acid, protein synthesis and DNA methylation in the human body, and is an essential micronutrient for the h...

Похожие товары

	Shecare HCG Pregnancy Rapid Test Dipstick Strips	Продавец: Shecare-ikangtai	Smart HCG Test Strips The working principle of pregnancy test using hcg urine test dipstickis to...
	Shecare Fetal Heart Beat Monitor	Продавец: Shecare-ikangtai	Fetal Heart Beat Monitor Apply appropriate coupling agent, slowly move the baby heartbeat with p...
	Shecare Digital Thermometer Manufacturer	Продавец: Shecare-ikangtai	Digital Thermometer 【Accurate & Fast Reading】 The Shecare Digital Oral Thermometer, Switchab...
	Shecare COVID-19 IgG/IgM Test Kit	Продавец: Shecare-ikangtai	COVID-19 IgG/IgM Test Kit COVID 19 test kit(Whole Blood/Serum/Plasma) is a solid phase immunochr...
	Shecare Smart Test Strip Recognition SaaS SDK	Продавец: Shecare-ikangtai	Based on millions of user data, the ‘Attention’ mechanism & ‘Deep Learning ...