Preparative Liquid Chromatography System

• 

Hanbon preparative liquid chromatography system has the characteristics of high efficiency, high speed, high automation, and explosion-proof, and is widely used in the separation and purification of pharmaceutical intermediates, biopharmaceuticals, synthetic drugs, natural products, fine chemicals, food additives and other fields. Including: CS-Prep® industrial preparative adsorption hplcsystem, Newstyle® laboratory liquid chromatography system, Intepure™ Integrated liquid chromatograph etc.

The Difference Between Analytical And Preparative Hplc System

Analytical chromatography, reflecting the composition of the sample, seeks efficient separation and high sensitivity without the need to collect specific fractions, and eluates are usually disposed of as waste liquids. In preparative process chromatography, however, the maximum amount of product must be produced in the minimum amount of time in order to save investment and operating costs. Due to the difference in purpose, there are major differences in the optimisation of the operating parameters chosen for preparative chromatography and analytical chromatography, including column size, packing, flow rate, operating pressure, injection volume, product purity, product recovery and chromatographic separation effectiveness. The former requires the smaller the injection volume, while the latter requires the column to be overloaded in order to increase the preparation volume. There are two types of column overloading, one is "mass overloading", where a smaller injection volume is maintained and the injection concentration is increased, and the other is "volume overloading", where a smaller injection concentration is maintained and the injection volume is increased. In preparative chromatography, mass overloading is generally considered to be preferable. In preparative chromatography separations, both separation and column efficiency decrease as the degree of mass overloading increases. However, operating with mass overload can increase the preparative volume provided that the separation can be achieved.

Preferred Options For Impurity Preparation

Impurity studies are carried out throughout the life cycle of pharmaceutical development. Impurity preparation is one of the bitter seas of sample purification, and the traditional approach is to use glass chromatography columns or analytical or semi-preparative HPLC to enrich bit by bit. The DAC50 with NS4210 chromatography system is 5-20 times more efficient than a 20 ml/min system with high throughput screening + excellent batch reproducibility. The system can also be equipped with an optional automatic fraction collector to increase automation and allow more focus on drug development.

For more informationabout hplc chromatography stepsand latest hplc instruments, please feel free to contact us!

Другие товары поставщика

	Chromatography System	Hanbon advanced chromatography systemshas reliable performance and flexible configuration, and can provide Bio-Lab® laboratory chromatography s...
	Membrane Cassette Holders	Membrane filter holderare package holders for deep filtration, ultrafiltration, and nanofiltration that range in size from 0.1 m² to 20 m²...
	Preparative HPLC	Hanbon offers Hanbon preparative HPLCand MPLC from laboratory to industrial level, which are essential tools for the isolation and purification of ...
	Biopharmaceutical Equipment and Devices	Hanbon is a manufacturer of liquid ssmb chromatographyseries products with a large production scale and a complete range of products in China. T...
	MCC® Manual Chromatography Column	MCC® adopts the compression way by manual screw to load packing materials, with the advantages of concise configuration , easy for cleaning and ...

Похожие товары

	Medical Splint RDJ013	Продавец: Hengshui Runde Medical Instruments Co.,Ltd	Medical Splint RDJ013 This medical aluminum splintis made of two layer IXPE and core aluminum al...
	Chest Seal	Продавец: Hengshui Runde Medical Instruments Co.,Ltd	Chest Seal The chest sealis an advanced occlusive wound dressing for open chest wounds. Thisches...
	Israel Bandage RDJ020	Продавец: Hengshui Runde Medical Instruments Co.,Ltd	Israel Bandage RDJ020 Israel BandageRDJ020is an Israeli battle dressingwith non-adhesive dressin...
	Gen 7 Tourniquet RDJ006	Продавец: Hengshui Runde Medical Instruments Co.,Ltd	Gen 7 Tourniquet RDJ006 Tourniquet Gen 7 tourniquet is a first aid and medic gearitemthat has be...
	First Aid Kit	Продавец: Hengshui Runde Medical Instruments Co.,Ltd	First Aid Kit This First Aid Kitis designed for rapid, effective emergency response in severe tr...