TM Widely-Targeted Metabolomics
TM high resolution metabolomics is the 'Untargeted metabolomics + Targeted Metabolomics' process that achieves the perfect combination of high resolution, wide-coverage, high sensitivity, and precise quantification. It is a great starting point to examine the global metabolite profile. Metware's curated database of 280,000 metabolites, which includes 3000 metabolites not found in public databases, allows more annotations from high-resolution mass spec data.
Technology Introduction
"TM" Widely-Targeted Metabolomics combines Untargeted metabolomics and Targeted metabolomics to achieve the perfect combination of high-resolution, wide-coverage, high-sensitivity, and precise quantification. Metware's patented Widely-Targeted Metabolomics technology stands out from many others with features such as:
Using high-resolution mass spectrometers to allow the unbiased collection of MS/MS spectrum data;
Metabolite discovery through global annotation of untargeted metabolom database with over 3000+ in-house metabolite database providing more metabolite annotation;
Using MRM analysis from QQQ to accurately quantify metabolites in each sample.
TM Widely-Targeted Matabolomics Service Technical Features
Large Curated Database
Collected ultra-high resolution data of over 280,000 metabolites. Each sample can typically identify over 1400 metabolites.
Rigorous Quality Control
A mature quality control system monitoring all aspects of experimentation from sample preparetion to data analysis.
Experienced
Stable and tested sample preparation protocol stemming from processing over a million samples a year.
Accurate Identification
Combining AB SCIEX QTOF 6600+ ultra-high resolution mass spectrum with our large curated database to achieve accurate metabolite identification.
Accurate Quantification
Using MRM mode from AB SCIEX Triple Quad 6500+ to achieve accurate relative quantification of metabolites.
Applications of TM Widely-Targeted Matabolomics Service
Clinical marker discovery and development
Understanding mechanisms behind disease progression
Studying drug efficacy and toxicity
Environmental toxicology research
For more information about targeted metabolomics workflow and metware library, please feel free to contact us!
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