Fondaparinux Sodium 114870-03-0 Low Molecular Weight Heparins

Fondaparinux is a synthetic pentasaccharide factor Xa inhibitor. Apart from the O-methyl group at the reducing end of the molecule, the identity and sequence of the five monomeric sugar units contained in fondaparinux is identical to a sequence of five monomeric sugar units that can be isolated after either chemical or enzymatic cleavage of the polymeric glycosaminoglycans heparinand heparin sulfate (HS). Within heparin and heparin sulfate this monomeric sequence is thought to form the high-affinity binding site for the anti-coagulant factor antithrombin III (ATIII). Binding of heparin/HS to ATIII has been shown to increase the anti-coagulant activity of antithrombin III 1000 fold. In contrast to heparin, fondaparinux does not inhibit thrombin.
Fondaparinux sodium is an antithrombotic anticoagulant, a Factor Xa inhibitor. Fondaparinux sodium is chemically related to low molecular weight heparins. Its pentasaccharide structure corresponds to the antithrombin III (ATIII) binding site of heparin. Fondaparinux sodium binding at this site potentiates the natural inhibitory effect of ATIII against factor Xa by a factor of approximately 300, which results in inhibition of thrombin generation.




Send product request

To: Shenzhen BST Science&Technology Co.,Ltd
Your E-mail:
Message text:


Send to other suppliers

Other supplier products

Myristoyl Pentapeptide-4 Cosmetic Peptides
Myristoyl Pentapeptide-4 Cosmetic Peptides INCI Name: Myristoyl Pentapeptide-4 Other names: Myristoyl Pentapeptide-4, Pal-KTTKS CAS: 214047-00-4 Appearance: Clear transparent liquid, low ...
Anti-Swelling Agent for Face and Body Sodium Dextran Sulfate 9011-18-1
Anti-Swelling Agent for Face and Body Sodium Dextran Sulfate 9011-18-1 INCI Name:  Sodium Dextran SulfateCas: 9011-18-1 Specification:Identity: To pass testAppearance:  White to off white powderSolubilit...
Acetyl Tetrapeptide-5 Cosmetic Peptides
Acetyl Tetrapeptide-5 Cosmetic Peptides INCI Name: Acetyl Tetrapeptide-5 cas: 820959-17-9 Appearance: Clear transparent liquid, low viscosity Peptide Content in liquid form:  100P...
Cosmetics Ingredient Trehalose Inci 6138-23-4 Moisturizing
Cosmetics Ingredient Trehalose Inci 6138-23-4 Moisturizing 1, Application for Cosmetics:Based on the property of retaining cell and bio-molecule activities, trehalose can be advantageously used as a desicca...
5-Methoxy-2-methylindole 1076-74-0
5-Methoxy-2-methylindole 1076-74-0 5-Methoxy-2-methylindole 1076-74-0 Name: 5-Methoxy-2-methylindole CAS: 1076-74-0 EC Number: 214-066-5 Formula: C10H11NO Molecular Weight: 161.20 Ap...
All supplier products

Same products

Buy pure Adinazolam CAS No: 37115-32-5;(prolfc.chem@gmail.com)
Buy pure Adinazolam CAS No: 37115-32-5;(prolfc.chem@gmail.com) Seller: Prolific Chem Co. Ltd. Quick Details: -Product Names: Adinazolam -Chemical Names: Deracyn, Adinazolamum -Molecular Formu...
BK-MDMA CAS No: 186028-79-5;(prolfc.chem@gmail.com)
BK-MDMA CAS No: 186028-79-5;(prolfc.chem@gmail.com) Seller: Prolific Chem Co. Ltd. Quick Details: -Product Name: BK-MDMA -Formal Name: 3,4-Methylenedioxymethcathinone (methylone) -...
mmb chminaca , MDMA BK-mdma , factory supply
mmb chminaca , MDMA BK-mdma , factory supply Seller: Hebei Yuanhua Biotechnology Co., Ltd Skype:Lily.335535 Whatsapp:+86-13231101361 Email:lily@hbyuanhua.com Hebei Yuanhua Biot...
L-fucose 2438-80-4  97% from Shanghai E-bio
L-fucose 2438-80-4 97% from Shanghai E-bio Seller: Shanghai E-bio Co.Ltd Fucose is a hexose deoxy sugar with the chemical formula C6H12O5. It is found on N-linked glycans...
LARGEST METHYLAMINE HYDROCHLORIDE SUPPLIER FACTORY IN CHINA
LARGEST METHYLAMINE HYDROCHLORIDE SUPPLIER FACTORY IN CHINA Seller: Hebei guanlang biotechnology co.,ltd PRODUCT: METHYLAMINE HYDROCHLORIDE(GET LATEST PRICE) CAS: 593-51-1 MOLECULAR FORMULA: CH6C...