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High quality Hydrogenated cinnamic acid (3-phenylpropionic acid) from Landmarkind

供应商: 731577

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来自Landmarkind的高品质氢化肉桂酸(3-苯基丙酸)
中文名称:清华肉桂Su
其他名字:
ARECHEM AL BO 0168;
苯丙酸;
benzenepropionicacid,氢化;
苯丙酸
; propanoicacid;
3-苯基;
4- propionicacid,3-苯基;
5- 3-苯基丙烷酸。
CAS号:501-52-0
分子式:C9H10O2

分子量:150.17
EINECS编号:207-924-5
纯度:≥98%
包装规格:25公斤/包装

使用限度:FEMA(mg / kg):饮料0.02~1.0;冷饮0.48~1.0;糖果0.80~4.0;烘焙食品17.0;凝胶,布丁,1.2;乳制品2.0; FDA,§172.515(2000):用量有限。用于配制香料的香料成分不得超过GB 2760中的最大允许量和最大允许残留量。
化学特性:白色棱形晶体。熔点48.5℃,沸点280℃,125-129℃(0.8kPa),相对密度1.071。易溶于热水,乙醇,苯,氯仿,乙醚,冰醋酸,石油醚和二硫化碳,微溶于冷水。它可以随水蒸气挥发。
用法:本品为香料调味剂。用作医药中间体,也用于有机合成。它可用作雷沙吉兰的中间体
储存:注意火源,特别是避免阳光照射,并存放在阴凉处。

关键词:氢化肉桂酸(3-苯基丙酸),香精,香料,合成香料,中间体药物,雷沙吉兰

描述:
氢化肉桂酸(3-苯基丙酸)是白色棱柱形晶体,熔点为48.5℃,沸点为280℃,125-129℃(0.8kPa),相对密度为1.071。易溶于热水,乙醇,苯,氯仿,乙醚,冰醋酸,石油醚和二硫化碳,微溶于冷水。它可以随水蒸气挥发。
帕金森病又称“震颤性麻痹”,是一种中枢神经系统退行性疾病,最常见于中老年人,被世界卫生组织列为“世界难治病”之一。随着社会的老龄化,中国帕金森病患者超过180万,发病率每年以0.1%的速度增长。由于没有合适的药物治疗,大约20-25%的患者最终丧生。能力。为了解决这个问题,2005年,丹麦LUNDBECK公司和以色列TEVA公司通过长期联合实验开发了一种雷沙吉兰。根据加拿大医学报的报告,与第一代治疗药物相比,雷沙吉兰治疗可以缓解帕金森病的症状长达6年,并且对神经也有一定的保护作用。但是,由于原料价格昂贵,制备方法复杂,雷沙吉兰的价格居高不下,病人也在苦苦挣扎。最新研究发现,雷沙吉兰是以低成本的氢化肉桂酸为中间体制备的。它具有操作简单,成本低,产量高的优点。 regagiran的价格比其他药物便宜。超过50%的患者为患者带来了新的希望。
此外,最近的国际化学研究所已经表明,氢化肉桂酸也可以用作治疗糖尿病药物格列本脲的中间体。糖尿病是一种世界性的顽固疾病,其外国的别名被称为“沉默的杀手”。目前中国有超过9200万糖尿病患者,另有1亿是潜在患者。格列本脲是口服降糖药最有效的药物,但由于原料价格昂贵且具有强毒副作用。在现代制药工业中,肉桂系列 - 氢化肉桂酸用作中间体,对减少副作用和降低血糖具有一定的辅助作用。


产品规格
项目要求结果
含量≥98%,98.3%
描述白色棱形晶体白色棱形晶体
熔化POIN 48-50℃,48.5℃下
旋转比1.5600-1.5710 1.5656
比重1.0-1.15 1.071
酸度≤1mgKOH/克0.4mgKOH / g的



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