Hydrogenated cinnamic acid

供应商: 726571


Molecular weight: 150.17

EINECS number: 207-924-5

Purity: ≥98%

Packing specification: 25 kg / packaging

Use limit: FEMA (mg / kg): beverage 0.02 ~ 1.0; cold drink 0.48 ~ 1.0; candy 0.80 ~ 4.0; baked goods 17.0; gel, pudding, 1.2; dairy products 2.0;FDA, §172.515 (2000): The amount is limited.The perfume ingredients used to formulate the fragrance must not exceed the maximum allowable amount and maximum allowable residue in GB 2760.

Chemical properties: white prismatic crystals. The temperature of 48.5° C, the boiling point of 280°C, 125-129°C(0.8 kPa), the relative density of 1.071. Soluble in hot water, alcohol, benzene, chloroform, ether, glacial acetic acid, petroleum ether and carbon disulfide, slightly soluble in cold water. It can volatilize with water vapor.

Usage: This product is a flavoring agent for spices. Used as a pharmaceutical intermediate, also used in organic synthesis.The it can be used as intermediate of rasagiline

Storage:Pay attention to the source of fire, especially to avoid sunlight, and store in a cool place.

Keywords: Hydrogenated cinnamic acid (3-phenylpropionic acid), flavors, spices, synthetic flavors, intermediate drug, rasagiline


Hydrogenated cinnamic acid (3-phenylpropionic acid) is a white prismatic crystal having a melting point of 48.5 °C, a boiling point of 280°C, 125-129°C(0.8 kPa), and a relative density of 1.071. Soluble in hot water, alcohol, benzene, chloroform, ether, glacial acetic acid, petroleum ether and carbon disulfide, slightly soluble in cold water. It can volatilize with water vapor.

Parkinson's disease, also known as "tremor palsy", is a central nervous system degenerative disease, most commonly found in middle-aged and elderly people, and is listed by the World Health Organization as one of the "world's difficult diseases." With the aging of the society, there are more than 1.8 million Parkinson's patients in China, and the incidence is increasing at a rate of 0.1% per year. Because there is no suitable medical treatment, about 20-25% of patients eventually lose their lives. ability. In order to solve this problem, in 2005, Denmark LUNDBECK company and Israel TEVA company developed a rasagiline through long-term joint experiments. Compared with the first generation of therapeutic drugs, according to the Canadian Medical Post report, rasagiline treatment can relieve the symptoms of Parkinson's disease for up to 6 years, and also has a certain protective effect on the nerves. However, due to the high price of raw materials and the complicated preparation methods, the price of rasagiline has remained high and the patients are suffering. The latest research found that rasagiline is prepared by using low-cost hydrogen cinnamic acid as an intermediate. It has the advantages of simple operation, low cost and high yield. The price of regagiran is cheaper than other drugs. More than 50% brings new hope to patients.

In addition, the recent International Institute of Chemistry has shown that hydrogenated cinnamic acid can also be used as an intermediate in the treatment of the diabetes drug glibenclamide. Diabetes is a worldwide stubborn disease, and its alias for foreign countries is called "silent killer." There are currently more than 92 million diabetic patients in China, and another 100 million are potential patients. Glibenclamide is the most effective drug for oral hypoglycemic, but it has been expensive due to the price of raw materials and has strong toxic side effects. In the modern pharmaceutical industry, the cinnamon series-hydrocinnamic acid is used as an intermediate, which has certain auxiliary effects on reducing side effects and lowering blood sugar.


至: 726571
Your E-mail:

Send to other suppliers

Other supplier products

P-Hydroxycinnamic Acid
P-Hydroxycinnamic Acid Molecular Weight: 164.16 EINECS: 231-000-0 Purity: ≥99% Appearance: White or light yellow powder Density: 1.07 Melting point: 218-221℃ Solubilit...
Ethyl cinnamate
Ethyl cinnamate Product name: Ethyl cinnamate Synonyms:2-propenoic acid; 3-phenyl-2-propenoicaciethylester CAS No: 103-36-6 Molecular Formula: c11h12o2 Molecular W...
 isopropyl cinnamate
isopropyl cinnamate Molecular Weight: 190.24 Boiling point: 268-270°C Density:1.028-1.0284g/mLat 25°C(lit.) Flash point:>110°C Refractive index:1.545-1....
Phenethyl cinnamate
Phenethyl cinnamate Molecular weight: 252.32 Purity: ≥99.9% MDL number: MFCD00022050 EC number: 203-120-3 Traits: white crystal, with aroma similar to rose cream Me...
3-(Trifluoromethyl)cinnamic acid
3-(Trifluoromethyl)cinnamic acid First aid measures 1 Description of first aid measures · General information: Immediately remove any clothing soiled by the product. ·...

Same products

CASCELL® IH 卖方: Cashem Advanced Materials Hi-tech Co.,Ltd Cascell®IH products are closed-cell rigid foams based on polymethacrylimide (PMI) chemistry,...
Ectoin 96702-03-3 Anti-Aging Ingredient
Ectoin 96702-03-3 Anti-Aging Ingredient 卖方: Shenzhen BST Science&Technology Co.,Ltd INCI Name: EctoinName: Ectoine,  (S)-2-Methyl-1,4,5,6-tetrahydropyrimidine-4-carboxylic acid, Thp...
Ergothioneine 497-30-3 Antioxidant
Ergothioneine 497-30-3 Antioxidant 卖方: Shenzhen BST Science&Technology Co.,Ltd Function: Antioxidant Anti-inflammatory Ultraviolet filter and protector   Applications Skin care...
Tungsten carbide tips for oilfield stabilizers
Tungsten carbide tips for oilfield stabilizers 卖方: 株洲弘通硬质合金有限公司 石油工业中用于扶正器的碳化钨钎刀片 由于碳化钨材料具有较高的硬度和强度,因此其耐磨性非常好。 它们被广泛用于许多不同的行业和应用程序中,甚至每天都有新的应用程序在发生。 我们拥有丰富的经验和...
PDC (Polycrystalline Diamond Compact) Cutter
PDC (Polycrystalline Diamond Compact) Cutter 卖方: Henan E-Grind Abrasives Co., Ltd. Polycrystalline diamond composite(PDC) E-Polycrystalline diamond composite(PDC) sheet is made of ...