Dexamethasone Palmitate
Synonyms: Dexamethasone-21-palmitate
CAS: 14899-36-6
Molecular formula: C38H59FO6
MW: 630.87
Packing: 5KG/TIN,2TIN/CTN
Unit: KG
Chemical Properties: Colourless Thick Oil
Usage: A corticosteroid prodrug for the treatment of eye disorders.
Abstract
PURPOSE:
Dexamethasone palmitate (DXP) is a lipophilic prodrug of dexamethasone (DXM), a potent corticosteroide used to treat a variety of ophthalmic diseases. The aim of the study was to characterize the sustained release capacity (in rabbit), efficacy (in rat and rabbit), and safety (in rabbit, cat, and minipig) of intravitreal (IVT) DXP emulsions in preclinical models.
