Nisin

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Jiangsu Yiming Biological Technology Co., Ltd., founded in August 1998, is a high-tech enterprise integrating R&D, manufacturing and sales. It boasts three modernized factories covering a total area of 175,000 m2 in Jiangsu province. It also has an R&D base with a team of more than 30 professional researchers. The company is now a member of the China Food Additives & Ingredients Association (CFAA) and China Biotech Fermentation Industry Association (CBFIA). The company mainly engaged in bio-engineering covering food enhancerand ingredients, medicine and other fields. It have natural preservatives for beverages, sausage binder, curdlan in food, yoghurt enzymes,etc.

Nisin isa polycyclic antibacterial peptide produced by the bacterium Lactococcus lactis that is used as a food preservative. It is soluble in water and can be effective at levels nearing the parts-per-billion range.

Nisinis a rare example of a "broad-spectrum" bacteriocin effective against many gram-positive organisms. Therefore, it can act as food preservatives in thermal-treatment food products including various pasteurised dairy products, canned vegetables, hot baked flour products, etc.

Nisin in cheesehas been approved as a natural food preservative by more than 60 other countries. In April 1988, it was recognized as the Generally Regarded as Safe (GRAS) by the U.S. Federal Register.

Key Benefits of Nisin

Extend shelf life

Prevent food spoilage caused by gram-positive bacteria

Shorten food sterilization time

Lower sterilization temperature

No impact on taste and flavor

Nisin FAQs

Is nisin safe?

Nisin is listed as a “natural preservative” in chemical dictionaries. It is approved as a natural food preservative by the Food and Agriculture Organization, WHO and the European Union.

How to apply nisin in the food industry?

Nisin is used in processed cheese, meats, beverages, etc. during production to extend shelf life by suppressing gram-positive spoilage and pathogenic bacteria. In foods, it is common to use nisin at levels ranging from 1~25 ppm, depending on the food type and regulatory approval.

Which pathogens can nisin act against?

Nisin is a rare example of a “broad-spectrum” bacteriocin effective against many gram-positive organisms, including lactic acid bacteria (commonly associated to avoid food spoilage), Listeria monocytogenes (a known pathogen), staphylococcus aureus, bacillus cereus, clostridium botulinum, etc. It is also particularly effective against spores.

What are the storage conditions of nisin?

Nisin has a limited shelf life. You need to keep it at cool temperatures or refrigerated until you use it. Once it is opened, you need to wrap it tightly and store it in the freezer.

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