Exemestane
Product Name:Exemestane
Synonyms:Aromasin;6-methylenandrosta-1,4-diene-3,17-dione;6-methyleneandrosta-1,4-diene-3,17-dione;10,13-dimethyl-6-methylidene-7,8,9,10,11,12,13,14,15,16-decahydrocyclopenta[a]phenanthrene-;FCE-24304;Exemestan;Exemestance
CAS:
MF:C20H24O2
MW:296.4
MP:190 ~ 192℃
Storage Temp. :Store at -20°C
Chemical Properties:white to light yellow crystal powder
Usage: Labeled Exemestane, intended for use as an internal standard for the quantification of Exemestane by GC- or LC-mass spectrometry.
Indications: Suitable for estrogen and progesterone receptor positive postmenopausal women with advanced breast cancer.
Usage and dosage: 25mg for 1 time per day, oral admiration after meals. For patients with mild hepatic and renal insufficiency, it is not required to adjust the dosage of the drug.
Uses
1). The second generation aromatase inhibitors, used for the treatment of metastatic breast cancer and used as adjuvant therapy for early breast cancer.
2). Pharmaceutical raw materials, is a kind of irreversible steroid body aromatase extinguishing agent, can inhibit the synthesis of estrogen, and reduce circulating estrogen levels, applicable to the progression of disease after treatment with tamoxifen in postmenopausal patients with advanced breast cancer.
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