Triptorelin

1) Triptorelin Details:

Name:Triptorelin
CAS: 57773-63-4
MF: C64H82N18O13
MW: 1311.45
1AppearanceWhite or slightly yellowish powder White powder
2SolubilitySoluble in water or 1% acetic acid at a concentration of 1mg/ml to give a clear, colorless solutionConforms
3Identity by HPLCThe retention is same with the reference substanceConforms
4Specific Optical Rotation-65.0- -75.0° (c=0.5, 95%HAc)-71.3°
5Amino Acid Composition± 10% of theoreticalConforms
6Peptide Purity (By HPLC)≥ 98.0% by area integration98.8%
7Related Substance (By HPLC)Total Impurities(%) ≤ 2.0% Largest Single Impurity (%) ≤ 1.0%1.2% 0.7%
8Acetate Content≤ 15.0%13.8%
9Water Content (Karl Fischer)≤ 5.0%1.5%
Usage promoting ovulation.

Description

Triptorelin,Hormone Peptides Triptorelin , a decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2) , is a -releasing hormone agonist (GnRH agonist) used as the acetate or pamoate salts . By causing constant stimulation of the pituitary , it decreases pituitary secretion of luteinizing hormone (LH) and follicle stimulating hormone (FSH) . Like other GnRH agonists , triptorelin may be used in the treatment of hormone-responsive cancers such as prostate cancer or breast cancer , precocious puberty , estrogen-dependent conditions (such as endometriosis or uterine fibroids) , and in assisted reproduction .

Triptorelin Usage:

Triptorelin is usually given as an injection at your doctor's office, hospital, or clinic. If you will be

using triptorelin at home, a health care provider will teach you how to use it. Be sure you understand

how to use triptorelin. Follow the procedures you are taught when you use a dose. Contact your

health care provider if you have any questions.
Triptorelin is injected into the muscle.
Rotate the injection site. Do not inject into an area of skin that is red, hard, or bruised, or has scars

r stretch marks.
Do not use triptorelin if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
Keep this product, as well as syringes and needles, out of the reach of children and away from pets.

Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of

these materials after use.

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