Coluracetam
Classification:OtherChemicals
CasNO.:
MolecularFormula:C19H23N3O3
MeltingPoint:
BoilingPoint:634.1°Cat760mmHg
Stability:null
Refractiveindex:1.64
FlashPoint:337.3°C
Purity:99
Appearance:null
usage:anootropicdrugoftheracetamfamily
BrandName:myland
EINECS:
Aliase:N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide.
Purity:99
Appearance:whitecrystallinepowder
Brand:myland
Packaging&Delivery
PackagingDetail:1kg/bag.
DeliveryDetail:
DetailedDescription
Productname:Coluracetam
Chemicalname:N-(2,3-Dimethyl-5,6,7,8-tetrahydrofuro[2,3-b]quinolin-4-yl)-2-(2-oxopyrrolidin-1-yl)acetamide.
CAS:
Purity:99%
Appearance:whitecrystallinepowder
Package:1kg/bag.
Coluracetam(BCI-540)isanootropicdrugoftheracetamfamily.Coluracetam(formerlyknownasMKC-231)wasinitiallydevelopedandtestedbytheMitsubishiTanabePharmaCorporationforAlzheimer'sdisease.Afterthedrugfailedtoreachendpointsinitsclinicaltrialsitwasin-licensedbyBrainCellsIncforinvestigationsintomajordepressiondisorder(MDD),afterbeingawardeda"QualifyingTherapeuticDiscoveryProgramGrant"bythestateofCalifornia.FindingsfromitsPhase2aclinicaltrialshavesuggestedthatitwouldbeanidealmedicationforco-morbidMDDwithgeneralizedanxietydisorder(GAD).BrainCellsInciscurrentlyout-licensingthedrugforthispurpose.Itmayalsohavepotentialuseinpreventionandtreatmentofischemicretinopathyandretinalandopticnerveinjury.
Coluracetamenhanceshigh-affinitycholineuptake(HACU)whichistherate-limitingstepofacetylcholine(ACh)synthesis,andistheonlyknowncholineuptakeenhancertocurrentlyexist.StudieshaveshownColuracetamtoimprovelearningimpairmentonasingleoraldosegiventoratswhichhavebeenexposedtocholinergicneurotoxins.Subsequentstudieshaveshownthatitmayinducelong-lastingprocognitiveeffectsbychangingthecholinetransporter
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