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Sildenafil, sold as Viagra and other trade names, is a medication used to treat erectile dysfunction and pulmonary arterial hypertension.Its effectiveness for treating sexual dysfunction in women has not been demonstrated.
It acts by inhibiting cGMP-specific phosphodiesterase type 5 (PDE5), an enzyme that promotes degradation of cGMP, which regulates blood flow in the penis.
Other potential effects of Viagra
Jet lag - Patricia V. Agostino, Santiago A. Plano, and Diego A. Golombek, from the Universidad Nacional de Quilmes, Argentina, were awarded the ig Nobel Prize in Aviation for discovering that Viagra helped hamsters recover from jet lag. (PNAS, 2007)
Exercise capacity - some athletes take Revatio to increase their exercise capacity, although evidence of its efficacy in this regard is scant.
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