COVID-19 Solutions

COVID-19 Detectionand SARS-CoV-2 Detection

As we know the COVID-19 pandemic is a scientific, medical, and social challenge. The syndrome coronavirus 2 (SARS-CoV-2) can rapidly develop, causing severe and deadly complications. The sars rapid testis an important method of dealing with the pandemic. The identification of effective laboratory biomarkers able to classify patients based on their risk is imperative in being able to guarantee prompt treatment. Analysis of recently published studies suggests that systemic vasculitis and cytokinin-mediated coagulation disorders are major factors in multiple organ failure in patients with severe covid-19 testingcomplications.

The following biomarkers have been identified: hematological (lymphocyte count, neutrophil count, neutrophil-lymphocyte ratio (NLR)), inflammatory (C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), procalcitonin (PCT)), immunological (interleukin (IL)-6 and biochemical (D-dimer, troponin, creatine kinase (CK), aspartate aminotransferase (AST)), especially those related to coagulation cascades in disseminated intravascular coagulation (DIC) and acute respiratory distress syndrome (ARDS). Genrui offers a variety of multi biomarkers detection options and products including the Hematology analyzer, Specific Protein Analyzer series, the chemistry analyzer series and POCT's Quantitative Immunoassay Analyzer.

References:

Ponti G, Maccaferri M, Ruini C, Tomasi A, Ozben T. Biomarkers associated with COVID-19 disease progression. Crit Rev Clin Lab Sci. 2020 Sep;57(6):389-399. DOI: 10.1080/10408363.2020.1770685. Epub 2020 Jun 5. PMID: 32503382; PMCID: PMC7284147.

Kermali M, Khalsa RK, Pillai K, Ismail Z, Harky A. The role of biomarkers in the diagnosis of COVID-19 - A systematic review. Life Sci. 2020 Aug 1;254:117788. DOI: 10.1016/j.lfs.2020.117788. Epub 2020 May 13. PMID: 32475810; PMCID: PMC7219356.

COVID-19 Solutions Types

Pre-processing System SP9600

SP9600 is a brand-new automated sample transfer processing system that can transfer 96 samples from closed tubes to a 96-well plate in 20-30 minutes.

Pre-processing System SP9600

Nucleic Acid Extraction

Our instrument uses the magnetic bead nucleic acid extraction method, with fully automatic, integrated, high extraction rate, super high-speed characteristics.

Fully Auto Nucleic Acid Extraction Instrument NE48

Fully Auto Nucleic Acid Extraction Instrument NE96

Nucleic Acid Extraction Reagents

Nucleic Acid Detection

The Real-Time Fluorescence Quantitative PCR Instrument has automatic integration, simple operation，fast detection speed，high sensitivity and other advantages. The gold standard for COVID-19 diagnosis is a dem...

Nucleic Acid Detection Instrument NX-8F

Nucleic Acid Detection Reagents

Rapid Test

Genrui has COVID-19 antigen test, COVID-19 antibody test, COVID-19 rapid test and other covid 19 test kits, with extremely high accuracy and can display the detection results within 20 minutes.

Colloidal Gold Rapid Test

Immunofluorescence Test

Infrared Thermometer JRT200

Infrared Thermometer's test Temperature range: 32-42.9 ℃ in COVID-19 pandemic can greatly, Avoid personnel contact, and reduce the transmission route of COVID-19 virus.

What is the COVID-19?

The viruses that cause COVID-19 are in the coronavirus group. Under microscopy, these organisms can be identified through their coronary shape. The lung diseases SARS and MERS are also caused by a virus in the group. Only a few people are immune to the currently popular novel coronavirus; so it has caused a considerable number of victims. Most infected people have only mild discomfort and will subside in a few days.

The symptoms of the coronavirus infection include:

Cough

Fever

Headache

loss of taste or smell

Repeated shaking with chills

Sore throat

Shortness of breath

Muscle pain

Some people have a worse course. COVID-19 may then be related to severe respiratory problems, pneumonia, high fever, and severe breathing difficulties. Not all patients with severe COVID-19 symptoms can survive. Older people are at higher risk of severe illness, as with previous diseases such as cataracts. For example cardiovascular disease, cancer or diabetes. Therefore, COVID-19 testing is becoming a common thing in people's daily lives.

D-dimer level in COVID-19 infection

According to several studies from three databases, Scopus, PubMed, and Web of Science have shown Abnormal coagulation function has been demonstrated to be involved in the disease progression of COVID-19, elevated D-dimer in COVID-19 patients is associated with higher mortality.

Patients with severe COVID-19 have a higher level of D-dimer than those with non-severe disease, and D-dimer greater than 0.5 μg/ml is associated with a severe infection in patients with COVID-19.

Expert opinion: D-dimer level is one of the measures used in patients to detect thrombosis. Studies have reported an increase in D-dimer and fibrinogen concentrations in the early stages of COVID-19 disease a 3 to 4-fold rise in D-dimer levels are linked to poor prognosis. In addition, underlying diseases such as diabetes, cancer, stroke, and pregnancy may trigger an increase in D-dimer levels in COVID-19 patients. Measuring the level of D-dimer and coagulation parameters from the early stage of the disease can also be useful in controlling and managing COVID-19 disease.

Genrui offers a variety of D-dimer detection options and products including the Specific Protein Analyzer series, the chemistry analyzer series and POCT's Quantitative Immunoassay Analyzer.

Other Biomarker of IVD Solutions

As we know the COVID-19 pandemic is a scientific, medical, and social challenge. The syndrome coronavirus 2 (SARS-CoV-2) can rapidly develop, causing severe and deadly complications.

The identification of effective laboratory biomarkers able to classify patients based on their risk is imperative in being able to guarantee prompt treatment.

Analysis of recently published studies suggests that systemic vasculitis and cytokine-mediated coagulation disorders are major factors in multiple organ failure in patients with severe COVID-19 complications.

The following biomarkers have been identified: hematological (lymphocyte count, neutrophil count, neutrophil-lymphocyte ratio (NLR)), inflammatory (C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), procalcitonin (PCT)), immunological (interleukin (IL)-6 and biochemical (D-dimer, troponin, creatine kinase (CK), aspartate aminotransferase (AST)), especially those related to coagulation cascades in disseminated intravascular coagulation (DIC) and acute respiratory distress syndrome (ARDS).

Genrui offers a variety of multi biomarkers detection options and products including the Hematology analyzer, Specific Protein Analyzer series, the chemistry analyzer series and POCT's Quantitative Immunoassay Analyzer.

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