Hydroxy Propyl Methyl Cellulose Capsules(material)
1.Material:HPMC(HydroxyPropylMethylCellulose,nowcommonlyknowashypromellose)isthemainmaterialusedinproducingemptyvegetablecapsules.Hydroxypropylmethylcellulose(HPMC)isproducedbysyntheticmodificationofthenaturallyoccurringpolymercelluloseandisconsideredsafefornormalconsumptioninhumans.ThematerialsDishengusedforproductionofvegetablecapsulesmeetsUSP,EP.Nowadayshypromellose(HPMC)hasbeenextensivelyandsuccessfullydevelopedintotwo-piececapsulesforuseinthepharmaceuticalandnutritionalindustries.2.Advantage:Importantbenefitsofhpmccapsuleincludeamoisturecontentofapproximately4%-6%makingitanexcellentcontainerformoisture-sensitivedrugs.HPMCvegetablecapsulesarealsolesspronetobrittleness.Additionally,hypromellosedoesnotbindtoitself,therefore,dissolutiondelaysduetocrosslinkingarenotanissue.Hypromelloseisaplant-derivedmaterialand,therefore,meetstheneedforcertainreligious,cultural,anddietaryrestrictions. |
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