Curcumin

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Name: Curcumin EINECS: 207-280-5 Molecular Formula: C21H20O6 CAS Registry Number: 458-37-7 Synonyms: 1,6-Heptadiene-3,5-dione, 1,7-bis(4-hydroxy-3-methoxyphenyl)-, (E,E)-; 1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione; diferuloylmethane; C.I. 75300; C.I. natural yellow 3; curouma; E-100; gelbwurz; Haidr; Halad; haldar; Halud; indian saffron; kachs haldi; merita earth; Natural Yellow 3; safra d'inde; souchet; terra merita; tumeric yellow; yellow ginger; yellow root; YO-KIN InChI: InChI=1/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3/b7-3+,8-4+ HS Code: 29145000 Molecular Structure: This structure is also available as a 2d Mol file Chemical Properties Appearance: orange crystalline powder Molecular Weight: 368.38 Density: 0.93 Boiling Point: 591.4 °C at 760 mmHg Melting Point: 183℃ Flash Point: 208.9 °C Storage Temperature: ?20°C Refractive index: 1.4155-1.4175 Solubility: Water solubility: Slightly soluble (hot) Biological Activity: Antitumor, anti-inflammatory and antioxidant agent. Downregulates expression of reactive-oxygen-generating enzymes (cyclooxygenase, lipoxygenase, iNOS), TNF α , IL-1, IL-6, PKC, EGFR, NF- κ B, I κ B kinase and more. Upregulates expression of PPAR γ , p53, Nrf2. Also displays antimicrobial, antidiabetic neuro- and cardioprotective properties in vivo . Stability: Stable, but may be light sensitive. Incompatible with strong oxidizing agents. Usage: For preparing curcuma paper, ph range 8-9, in detection of boron.



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