High quality BOC-L-GLU(ME)-OME
BOC-L-GLU(ME)-OME is one of the core starting materials for the synthesis of the oral anti-coronavirus drug parovetide (PF-07321332), which is used to construct the key chiral pyrrolidine ring structure in the drug molecule. Through steps such as condensation with bromoacetone, cyanide reduction, intramolecular amide hydrolysis cyclization, and deprotection to form salts, the key intermediate (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl] propionic acid methyl ester of parovetide can be efficiently prepared. The design of the chiral center and the protection group enables precise control of the stereospecificity of the cyclization reaction, ensuring the configuration purity of the drug molecule. This is an important foundation for achieving the large-scale synthesis of parovetide and reducing production costs.
Other supplier products
|
|
Glycyl-glycyl-glycine Partners, long-term cooperation |
Glycyl-glycyl-glycine helps improve the texture and stability of foodMeat product processingApplication scenarios: ham sausages, sausages, braised ... |
|
|
L-Alanyl-L-cystine |
Role and Application of L-Alanyl-L-cystine Biomedical Research: It can be used to study protein structure - function relationships and peptide - re... |
|
|
High purity Cystine Disodium Salt |
The disulfide bond (-S-S-) and ionic functional groups of Cystine Disodium Salt provide flexible and controllable chemical reactivity, making it a ... |
|
|
L-Cysteine S-Sulfate Na Price |
Density and Bulk Properties of L-Cysteine S-Sulfate Na Crystal density: The crystal density of the purified product is approximately 1.65–1.7... |
|
|
Cystine Disodium Salt Powder |
As a salt of a dibasic amino acid, Cystine Disodium Salt exhibits typical amphoteric characteristics, with its ionization state closely dependent... |
All supplier products
Same products
