BOC-L-GLU(ME)-OME

BOC-L-GLU(ME)-OME is one of the core starting materials for the synthesis of the oral anti-coronavirus drug parovetide (PF-07321332), which is used to construct the key chiral pyrrolidine ring structure in the drug molecule. Through steps such as condensation with bromoacetone, cyanide reduction, intramolecular amide hydrolysis cyclization, and deprotection to form salts, the key intermediate (S)-2-(Boc-amino)-3-[(S)-2-oxo-3-pyrrolidinyl] propionic acid methyl ester of parovetide can be efficiently prepared. The design of the chiral center and the protection group enables precise control of the stereospecificity of the cyclization reaction, ensuring the configuration purity of the drug molecule. This is an important foundation for achieving the large-scale synthesis of parovetide and reducing production costs.

Other supplier products

	L-Aspartic acid monosodium salt monohydrate	While L-Aspartic acid monosodium salt monohydrate is generally recognized as safe (GRAS) by global regulatory bodies (e.g., FDA in the U.S., EFSA i...
	Bulk supply	Cosmetic and Nutraceutical Fields of L-Alanyl-L-cystine 1. Skin Health Supplements Due to its cysteine content, it may be included in oral or topic...
	Hydantoin	Hydantoin in Cosmetic IndustryPreservatives: Hydantoin derivatives such as DMDM hydantoin are used as preservatives in cosmetics and personal care ...
	Glycyl-glycine	Glycyl-glycine provides support for metabolic health Emerging research suggests potential benefits in metabolic contexts: As a glycine precursor, g...
	L-Cysteine S-Sulfate Na	Solubility of L-Cysteine S-Sulfate NaWater solubility: It is highly soluble in water with good dissolution performance. At 25 °C, the solubilit...

供应产品

Same products

	Glycine	卖方: Shanghai Yifu Food Ingredients Co., Ltd	Glycine is a non-essential amino acid naturally present in the human body and is also a substance...
	Glycine	卖方: Shanghai Yifu Food Ingredients Co., Ltd	Glycine is an endogenous amino acid in the human body and a fundamental component of proteins. It...
	Glycine	卖方: Shanghai Yifu Food Ingredients Co., Ltd	Glycine is a food-grade amino acid approved by the state. Due to its high safety, sweet taste, an...
	Glycine	卖方: Shanghai Yifu Food Ingredients Co., Ltd	Glycine has three reaction centers: amino group, carboxyl group, and methylene group. It has typi...
	Glycine Supply price	卖方: Shanghai Yifu Food Ingredients Co., Ltd	Physical properties of glycine1. Appearance and OdorAt room temperature, it is a white crystallin...