16-Alpha-Hydroxy Prednisolone CAS : 13951-70-7
16-Alpha-HydroxyPrednisolone
CAS:13951-70-7
MolecularFormula:C21H28O6
FormulaWeight:376.44
HSCode:3006601000
MDensity:1.38g/cm3
BoilingPoint(ºC):591.5°Cat760mmHg
FlashPoint(ºC):325.6°C
Refractive_index:1.629
Appearance:Whiteorwhitecrystallinepowder
OLFile:Molfile
Purity:98%
Character:WhitePowder
Standard:GMP,ISO,UP,SP
Storage:Keepitundersealincoolanddarkplace
Prednisoloneisasyntheticglucocorticoidineffect,similartotheeffectofprednisone,anti-inflammatory,anti-allergiceffects,itsstronganti-inflammatoryeffects,waterandsaltmetabolismweak.Thisproductisahydroxycompound(hydroxylgroupon11),preferablytopicalapplicationeffect,alsoappliestopatientswithliverdysfunction.Oralabsorptionquicklyandcompletely,onehourofpeakplasmaconcentration,plasmaproteinbindingrateof90%to95%,halflifeofabout200minutes.Canenterthefetalcirculation,itappearedinthedoseofmilkof0.07%to0.23%.Bylivermetabolism,mainlyfromthekidney,whichaccountedformorethan20%oftheprototypedrug.Suitableforthetreatmentofeczema,dermatitisandotherallergicdiseases,lupuserythematosus,dermatomyositisandotherconnectivetissuedisease
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