Eptifibatide
|
Product Name |
Eptifibatide; |
|
Sequence |
Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 |
|
Cas No. |
|
|
Molecular Formula |
C35H49N11O9S2 |
|
Molecular Weight |
832.4 |
|
Appearance |
White slightly yellwish powder |
|
Specific Rotation[20/D] |
-75.0～-95.0°（C=1，1%HAc） |
|
Amino Acids composition |
± 10% |
|
Peptide Purity (By HPLC) |
≥98% by area integration |
|
Related Substance (By HPLC) |
Total Impurities (%)≤2.0% Largest Single Impurity (%)≤ 1.0% |
|
Water Content (Karl Fischer) |
≤8.0% |
|
Peptide Content(N determination) |
≥80% |
|
Acetate Content |
≤15% |
|
IR spectrum |
in accordance |
Brief introduction:
Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class.[1] Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri).
It belongs to the class of the so-called arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market.
Indications
Eptifibatide is used to reduce the risk of acute cardiac ischemic events (death and/or myocardial infarction) in patients with unstable angina or non-ST-segment-elevation (e.g., non-Q-wave) myocardial infarction (i.e., non-ST-segment elevation acute coronary syndromes) both in patients who are to receive non surgery (conservative) medical treatment and those undergoing percutaneous coronary intervention (PCI).
The drug is usually applied together with aspirin or clopidogrel and (low molecular weight or unfractionated) heparin. Additionally, the usual supportive treatment consisting of applications of nitrates, beta-blockers, opioid analgesics and/or benzodiazepines should be employed as indicated. Angiographic evaluation and other intensive diagnostic procedures may be considered a first line task before initiating therapy with eptifibatide.
在线联系供应商
Other supplier products
 |
Dexamethasone Palmitate | Dexamethasone Palmitate Synonyms: Dexamethasone-21-palmitate CAS: 14899-36-6 Molecular formula: C38H59FO6 MW: 630.87 Packing: 5KG/TIN,... |
 |
Trenbolone Ace 10161-34-9 Finaplix / Revalor-H Powder Muscle Building Bulking Steroids | Basic Info Model NO.:10161-34-9 CAS No:10161-34-9 Einecs No:233-432-5 Purity:99% Trademark:Saichuang Another Name:Revalor-H; Finaplix Mf:C20h... |
 |
DSIP | Detail DSIP DSIP Unit Size :2 mg/vialDSIP Unit Quantity :1 VialDSIP Purity: 99.0%minDelta sleep-inducing peptide(DSIP)Sequence:r-l-Gly... |
 |
GHRP-2 Acetate | Product Name GHRP-2 Acetate Sequence Cas No. Molecular Formula C45H55N9O6 Molecular Weight 818.0 Purity (HPLC) ... |
 |
Testosterone Acetate | Testosterone Acetate Other name: testosterone acetate--dea schedule iii; (17beta)-3-oxoandrost-4-en-17-yl acetate; 3-oxoandrost-4-en-17-yl acetate ... |
Same products
 |
Fischer Tropsch wax used for the processing of leather care products | 卖方: Syntop chemical Co.,Ltd. | Fischer Tropsch wax plays a significant role in the formulation of leather care products, primari... |
 |
Alloy Steel Precision Cast Construction Machinery Parts | 卖方: NingBo YinZhou ChengEn Machinery CO.,Ltd. | Application ScenariosEarthmoving Machinery: Bucket teeth, boom connectors Mining Equipment: Crus... |
 |
Fischer Tropsch Wax with high melting point for adhesive | 卖方: Syntop chemical Co.,Ltd. | Fischer Tropsch wax is an ideal additive in adhesive processing, particularly in the field of EVA... |
 |
iFixes iT23 液晶屏开启器 | 卖方: 深圳市维客修科技有限公司 | iT23液晶屏开启器，安全便捷地修复iPhone X-17系列手机及平板屏幕电脑。 |
 |
High medium low melting point Fischer Tropsch wax for candle | 卖方: Syntop chemical Co.,Ltd. | Main Applications of Fischer-Tropsch Wax in Candle Manufacturing Enhancing Gloss and Aesth... |
