Eptifibatide
Product Name |
Eptifibatide; |
Sequence |
Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 |
Cas No. |
|
Molecular Formula |
C35H49N11O9S2 |
Molecular Weight |
832.4 |
Appearance |
White slightly yellwish powder |
Specific Rotation[20/D] |
-75.0~-95.0°(C=1,1%HAc) |
Amino Acids composition |
± 10% |
Peptide Purity (By HPLC) |
≥98% by area integration |
Related Substance (By HPLC) |
Total Impurities (%)≤2.0% Largest Single Impurity (%)≤ 1.0% |
Water Content (Karl Fischer) |
≤8.0% |
Peptide Content(N determination) |
≥80% |
Acetate Content |
≤15% |
IR spectrum |
in accordance |
Brief introduction:
Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class.[1] Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri).
It belongs to the class of the so-called arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market.
Indications
Eptifibatide is used to reduce the risk of acute cardiac ischemic events (death and/or myocardial infarction) in patients with unstable angina or non-ST-segment-elevation (e.g., non-Q-wave) myocardial infarction (i.e., non-ST-segment elevation acute coronary syndromes) both in patients who are to receive non surgery (conservative) medical treatment and those undergoing percutaneous coronary intervention (PCI).
The drug is usually applied together with aspirin or clopidogrel and (low molecular weight or unfractionated) heparin. Additionally, the usual supportive treatment consisting of applications of nitrates, beta-blockers, opioid analgesics and/or benzodiazepines should be employed as indicated. Angiographic evaluation and other intensive diagnostic procedures may be considered a first line task before initiating therapy with eptifibatide.
Отправить запрос, связаться с поставщиком
Другие товары поставщика
Antide Acetate | Product Name Antide Acetate Sequence Ac-D-2-Nal-p-Chloro-D-Phe-β-(3-pyridyl)-D-Ala-Ser-Lys(nicotinoyl)-D-Lys(nicotinoyl)-Leu-Lys(i... | |
Glucagon(1-29)(Human) | Product Name Glucagon(1-29)(Human) Sequence H-His-Ser-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Ser-Arg-Arg-Ala-Gln-Asp-Phe-V... | |
Gonadorelin Acetate | Product Name Gonadorelin Acetate Sequence Glp-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2 Cas No. 71447-49-9 Molecular Formula ... | |
Discreet Packing and Safe Delivery Oxytocin Acetat | Basic Info Model NO.:50-56-6 CAS:50-56-6 Molecular Weight:1007 Appearance:White Powder Specification:99% Oxytocin Acetate HS Code:2922199090 ... | |
Eledoisin Acetate | Product Name Eledoisin Acetate Sequence pGlu-Pro-Ser-Lys-Asp-Ala-Phe-Ile-Gly-Leu-Met-NH2 Cas No. 69-25-0 Molecular Formula ... |
Похожие товары
Резервуар с жидким азотом для Боснии и Герцеговины для лаборатории KGSQ | Продавец: Хэнань Тяньчжидао Биотехнология Лтд. | В лабораториях чаще всего используются резервуары с жидким азотом, имеющие большую вместимость, б... | |
Хранение сперматозоидов в Танзании Сосуд KGSQ ln2 | Продавец: Henan Tianzhidao Biological Technology Co., Ltd. | В лабораториях чаще всего используются резервуары с жидким азотом, имеющие большую вместимость, б... | |
Ebike Battery | Продавец: Shenzhen Worldpower Energy Storage Technology Co.,Ltd | Custom Ebike Lithium Battery Manufacturer Elevate your electric biking experience with Worldpowe... | |
Battery Energy Storage Systems | Продавец: Shenzhen Worldpower Energy Storage Technology Co.,Ltd | Battery Energy Storage Systems (BESS) are cutting-edge technologies that store electrical energy ... | |
ETH Ethereum Jasminer X4 BRICK ASIC Miner | Продавец: Shenzhen Dovina Electronic Co.,Ltd | Jasminer X4 Brick Review Jasminer x4 brick for salefrom Jasminer mining EtHash algorithm with a ... |