Paracetamol Tablets

Generic name: acetaminophen tablets English name: paracetamol Tablets The main component of this product is acetaminophen. 【Properties】 This product is a white piece. Chemical name: N-(4 - hydroxyphenyl) acetamide. Molecular formula: C8H9NO2 MW: 151.16 Pharmacology and toxicology This product is acetanilide class of antipyretic analgesics. Reach the antipyretic effect by inhibition of cyclooxygenase, selective inhibition of the hypothalamic thermoregulatory center of prostaglandin synthesis, resulting in peripheral vasodilatation, sweating, the strength of its antipyretic effects similar to aspirin; by inhibiting prostaglandin the synthesis and release play a role in analgesia improve pain threshold, belonging to the peripheral analgesic more effective than aspirin is weak, only mild to moderate pain effectively. This product has no anti-inflammatory effects. Pharmacokinetics] This product is rapidly absorbed after oral administration and completely absorbed in the body evenly distributed. 0.5 to 2 hours after oral administration, peak plasma concentration. Plasma protein binding rate is about 25% to 50%. This product is 90% to 95% metabolized in the liver, the major metabolite of glucuronic acid and sulfuric acid conjugates. Mainly in the form of glucuronidation, excretion from the kidneys within 24 hours, about 3% unchanged in the urine. The plasma half-life of l ~ 3 hours, renal insufficiency, the half-life is not affected, but patients with liver dysfunction and newborns, the elderly half-life is prolonged, and children has been shortened. Through the milk secretion. Indications Antipyretic and analgesic drugs for fever, headache, joint pain. Dosage Oral time 0.3 ~ 0.6g (l The first ~ 2 tablets), according to need day 3 to 4 times a day dosage should not exceed 2g (7 tablets). Antipyretic treatment is generally not more than three days, analgesic administration over 10 days straight. Children according to the weight of a 10 to 15mg/kg, every 4 to 6 hours; 12 children under the age of not more than five times every 24 hours dose regimen is not more than five days. This product is not long-term use. Adverse reactions Conventional doses, adverse reactions to acetaminophen rarely, occasionally can cause nausea, vomiting, sweating, abdominal pain, pale skin, and so on, a small number of cases can occur in atopic dermatitis (rash, pruritus, etc.), agranulocytosis, thrombocytopenia reduction in methemoglobinemia, anemia, liver and kidney dysfunction, and rarely cause gastrointestinal bleeding. Of taboos Patients with severe liver and kidney dysfunction, and those who are allergic to the chemicals disabled. Mail: kerry-doris@kerrypharm.com


在线询价

至: Kerry Industry Co., Ltd.
Your E-mail:
消息正文:


Send to other suppliers

Other supplier products

Metamizole Sodium Tablets
AM-2201
Oxalyl chloride
Mercury
Thiamethoxam
供应产品

Same products

Testosterone propionate
Testosterone propionate 卖方: Hubei Yuancheng Technology Company
	High-quality ceramic catalyst Coated precious metal
High-quality ceramic catalyst Coated precious metal 卖方: Jiuyuan Co.,Ltd ClassificationCatalystMF2MgO.2Al2O3.5SiO2Place of OriginGuangdong, China (Mainland)ApplicationEli...
	Ceramic Catalyst
Ceramic Catalyst 卖方: Jiuyuan Co.,Ltd ClassificationCatalystMF2MgO.2Al2O3.5SiO2Place of OriginGuangdong, China (Mainland)ApplicationEli...
TMF-20PE PE environmental friendly flame retardant masterbatch
TMF-20PE PE environmental friendly flame retardant masterbatch 卖方: HuiZhou Tomgfeel New Material Technology CO.,Ltd Polyethylene flame retardant masterbatch use of our patented technology and in strict accordance ...
TMF-088FR PP(Copolymer) Environmental Protection Flame Retardant
TMF-088FR PP(Copolymer) Environmental Protection Flame Retardant 卖方: HuiZhou Tomgfeel New Material Technology CO.,Ltd Highly efficient flame retardant is a new and efficient reaction type of environmentally friendly...