Phospho-L-Tyrosine Disodium Salt
Phospho-L-Tyrosine Disodium Salt in Cell Biology and Molecular Biology Research
Protein Interaction Studies: Used to probe interactions between phosphotyrosine-containing peptides/proteins and SH2 (Src homology 2) domain-containing proteins. For example, it verifies the binding affinity between phosphotyrosine motifs and SH2 domains in signaling adaptors (e.g., Grb2, PI3K), elucidating molecular recognition mechanisms in signal transduction.
Structural Biology: Employed as a ligand in X-ray crystallography or NMR studies to determine the 3D structure of phosphotyrosine-binding proteins (e.g., phosphatases, SH2 domain proteins). This aids in understanding how these proteins recognize and bind phosphorylated substrates at the atomic level.
Functional Validation of Phosphorylation Sites: Used in site-directed mutagenesis experiments to mimic constitutive phosphorylation at specific tyrosine residues in target proteins. By comparing the activity of wild-type vs. phosphomimetic mutants, researchers confirm the functional significance of individual phosphorylation sites (e.g., in enzyme activation or protein localization).
Other supplier products
|
|
Cystine Disodium Salt |
Cystine Disodium Salt, systematically named disodium (R,R)-3,3'-dithiobis(2-aminopropanoate), is an ionic derivative of L-cystine formed by neutral... |
|
|
Cystine Disodium Salt |
Cystine Disodium Salt is used as a standard reference material in biochemical analysis due to its high purity and stable chemical properties:
... |
|
|
Cystine Disodium Salt |
Cystine Disodium Salt, systematically named disodium (R,R)-3,3'-dithiobis(2-aminopropanoate), is a water-soluble ionic derivative of L-cystine&md... |
|
|
Glycyl-glycine |
Glycyl-glycine in Pediatric and Geriatric Nutrition In specialized nutritional products for vulnerable groups: For infants or children with immatur... |
|
|
Phospho-L-Tyrosine Disodium Salt |
In diagnostic reagent manufacturing, Phospho-L-Tyrosine Disodium Salt is incorporated into in vitro diagnostic (IVD) kits as a calibrator or contro... |
供应产品
Same products
