3-Bromocinnamic acid
Synonyms：RARECHEM BK HC T307;TRANS-3-BROMOCINNAMIC ACID;M-BROMOCINNAMIC ACID;M-BROMOPHENYLACRYLIC ACID;BROMOCINNAMIC ACID,3-;3-BROMOCINNAMIC ACID;AKOS BBS-00006566;AKOS B004044
CASNO.：32862-97-8
Formula：C9H7BrO2
Molecular weight: 227.05
EINECSNO.:251-267-7
Melting point: 177-179 °C
Appearance: Colorless crystal
Vapor pressure: 0.0±0.8 mmHg at 25°C
Refractive index: 1.648
Storage: Shading, confined preservation, dry, ensure good ventilation or exhaust in the workshop
Stability: Stable under normal temperature and pressure
Key words: 3-Bromocinnamic acid, spices, essence, Synthetic essence,
General description
3-Bromocinnamic acid is the metabolite of cinromide (3-bromo-N-ethylcinnamamide) and can be analysed in plasma by high-performance liquid chromatographic method.
Simultaneous determination of the anticonvulsants, cinromide (3-bromo-n-ethylcinnamamide), 3-bromocinnamamide, and carbamazepine in plasma by high-performance liquid chromatography.
3-Bromocinnamic acid is used as organic synthesis of raw materials, fine chemicals, pharmaceutical intermediates.
Abstract
A high-performance liquid chromatographic method is described for monitoring plasma concentrations of cinromide (3-bromo-N-ethylcinnamamide) and its de-ethylated metabolite. Carbamazepine levels can be easily measured by the same technique. The N-isopropyl analogue of cinromide is used as internal standard, and all compounds are easily separated on a reversed-phase column operated at 55 degrees with a small-diameter pre-column maintained at the same temperature. The extraction is rapid and generally applicable to plasma and urine samples that are to be analyzed by reversed-phase chromatography. Short- and long-term reproducibility studies show less than 4% relative standard deviation for replicate determinations for all drugs. Limits of quantitation are 10-20 ng/ml with an internal standard concentration of 3 micrograms/ml. Another metabolite of cinromide, 3-bromocinnamic acid, which may have some anticonvulsant effect, can be analyzed simultaneously by buffering the mobile phase and adding an ion-pairing reagent.Storage:Pay attention to the source of fire, especially to avoid sunlight, and store in a cool place.
Specifications
|
Item |
REQUIREMENT |
RESULT |
|
Assay |
≥99% |
|
|
Description |
Colorless crystal |
Whiteorslightlyyellowcrystal |
|
Meltingpoint |
177-179 °C |
178°C |
|
Rotationratio |
|
在线联系供应商
Other supplier products
 |
2-Bromocinnamic acid | Synonym: O-bromocinnamic acid; 2-bromocinnamic acid; 2-bromocinnamic acid; trans 2-bromocinnamic acid, 98+%, 98+%; trans 2-bromocinnamic acid; tran... |
 |
2-Methylcinnamic acid | Synonym: 2-METHYLCINNAMIC ACID;3-O-TOLYL-ACRYLIC ACID;METHYLCINNAMIC ACID,2-;o-Methylcinnamic acid;trans-2-Methylcinnamic acid;2-METHYLCINNAMIC ACI... |
 |
isobutyl cinnamate | CAS No.: 122-67-8 Formula: C13H16O2 Molecular Weight: 204.2649 Boiling point: 296.7°C at 760 mmHg Density:1.019 g/cm3 Flash point:157.2°C ... |
 |
2-Fluorocinnamic acid | CAS No.:451-69-4 Formula: C9H7FO2 Molecular Weight: 166.15 Melting point:178-180 °C(lit.) Boiling point: 281.6°C at 760 mmHg Density:1.28... |
 |
Cinnamamide | Name：Cinnamamide Other Names：Cinnamamide,predominantly trans;(Z)-3-phenylprop-2-enamide CAS No：621-79-4 EINECS No：210-707-8 Formula：C9H9NO Molar vo... |
Same products
 |
CAS 52190-28-0 | 卖方: big-reat | The following is a product list, if you are interested in my products, please feel free to contac... |
 |
CAS 49851-31-2 | 卖方: big-reat | The following is a product list, if you are interested in my products, please feel free to contac... |
 |
CAS 28578-16-7 PMK | 卖方: big-reat | 以下是产品清单，如果您对我的产品感兴趣，请随时与我联系！ CAS号：110-63-4 593-51-1 28578-16-7 5449-12-7 20320-59-6 1451-82... |
 |
CAS 5449-12-7 BMK | 卖方: big-reat | The following is a product list, if you are interested in my products, please feel free to contac... |
 |
CAS 1451-82-7 | 卖方: big-reat | The following is a product list, if you are interested in my products, please feel free to contac... |
