3-Bromocinnamic acid

• 
• 

Synonyms：RARECHEM BK HC T307;TRANS-3-BROMOCINNAMIC ACID;M-BROMOCINNAMIC ACID;M-BROMOPHENYLACRYLIC ACID;BROMOCINNAMIC ACID,3-;3-BROMOCINNAMIC ACID;AKOS BBS-00006566;AKOS B004044

CASNO.：32862-97-8

Formula：C9H7BrO2

Molecular weight: 227.05

EINECSNO.:251-267-7

Melting point: 177-179 °C

Appearance: Colorless crystal

Vapor pressure: 0.0±0.8 mmHg at 25°C

Refractive index: 1.648

Storage: Shading, confined preservation, dry, ensure good ventilation or exhaust in the workshop

Stability: Stable under normal temperature and pressure

Key words: 3-Bromocinnamic acid, spices, essence, Synthetic essence,

General description

3-Bromocinnamic acid is the metabolite of cinromide (3-bromo-N-ethylcinnamamide) and can be analysed in plasma by high-performance liquid chromatographic method.

Simultaneous determination of the anticonvulsants, cinromide (3-bromo-n-ethylcinnamamide), 3-bromocinnamamide, and carbamazepine in plasma by high-performance liquid chromatography.

3-Bromocinnamic acid is used as organic synthesis of raw materials, fine chemicals, pharmaceutical intermediates.

Abstract

A high-performance liquid chromatographic method is described for monitoring plasma concentrations of cinromide (3-bromo-N-ethylcinnamamide) and its de-ethylated metabolite. Carbamazepine levels can be easily measured by the same technique. The N-isopropyl analogue of cinromide is used as internal standard, and all compounds are easily separated on a reversed-phase column operated at 55 degrees with a small-diameter pre-column maintained at the same temperature. The extraction is rapid and generally applicable to plasma and urine samples that are to be analyzed by reversed-phase chromatography. Short- and long-term reproducibility studies show less than 4% relative standard deviation for replicate determinations for all drugs. Limits of quantitation are 10-20 ng/ml with an internal standard concentration of 3 micrograms/ml. Another metabolite of cinromide, 3-bromocinnamic acid, which may have some anticonvulsant effect, can be analyzed simultaneously by buffering the mobile phase and adding an ion-pairing reagent.Storage:Pay attention to the source of fire, especially to avoid sunlight, and store in a cool place.

Specifications

Другие товары поставщика

	Cinnamonitrile	Alias: Cinnamonitrilecistrans; 3-Phenylacrylonitrile; (2E)-3-phenylprop-2-enenitrile; (2Z)-3-phenylprop-2-enenitrile CAS Number: 1885-38-7; 4360-4...
	isopropyl cinnamate, 98	CAS No.: 7780-06-5 Formula: C12H14O2 Molecular Weight: 190.24 Boiling point: 268-270°C Density:1.028-1.0284g/mLat 25°C(lit.) Flash point:&...
	Cinnamoyl chloride	CAS No.:102-92-1 Molecular Formula:C9H7ClO Molecular Weight:166.604 g/mol Synonym:Cinnamoyl chloride;3-Phenyl-2-propenoyl chloride;3-Phenylpropeno...
	Potassium cinnamate	CAS No.: 16089-48-8 Formula: C9H7KO2 Usage: Mainly used for food preservation, and can also be used as a raw material for flavoring 【product trai...
	2-Fluorocinnamic acid	CAS No.:451-69-4 Formula: C9H7FO2 Molecular Weight: 166.15 Melting point:178-180 °C(lit.) Boiling point: 281.6°C at 760 mmHg Density:1.28...

Похожие товары

	CAS 52190-28-0	Продавец: big-reat	The following is a product list, if you are interested in my products, please feel free to contac...
	CAS 49851-31-2	Продавец: big-reat	The following is a product list, if you are interested in my products, please feel free to contac...
	CAS 28578-16-7 PMK	Продавец: big-reat	以下是产品清单，如果您对我的产品感兴趣，请随时与我联系！ CAS号：110-63-4 593-51-1 28578-16-7 5449-12-7 20320-59-6 1451-82...
	CAS 5449-12-7 BMK	Продавец: big-reat	The following is a product list, if you are interested in my products, please feel free to contac...
	CAS 1451-82-7	Продавец: big-reat	The following is a product list, if you are interested in my products, please feel free to contac...