White Crystalline Powder Pharmaceutical Intermediates Trilostane Cas 13647-35-3
White Crystalline Powder Pharmaceutical Intermediates Trilostane Cas 13647-35-3 Basic Info. Trilostane Synonym: Vetoryl CAS : 13647-35-3 Molecular Formula: C20H27NO3 Molecular Weight: 329.4333 Assay :99% Einecs No: 237-133-0 Grade : Pharmaceutical Grade Storage: Shading, confined preservation Appearance:: White crystalline powder Usage : Trilostane can inhibit cortical hormone in the process of synthesis of 3 beta dehydrogenase, make the cortisol, aldosterone synthesis decreased, clinically used in the treatment of Cushing syndrome (hypercortisolism) and primary aldosteronism. This product also had significantly effect to decreased serum testosterone level. Product Description: Trilostane is used in the treatment of Cushing's syndrome. It is normally used in short-term treatment until permanent therapy is possible. Trilostane blocks an enzyme involved in the production of several steroids including cortisol. Inhibiting this enzyme inhibits the production of cortisol. In Cushing's syndrome, the adrenal gland overproduces steroids. Although steroids are important for various functions of the body, too much can cause problems. Trilostane reduces the amount of steroids produced by the adrenal gland. Trilostane produces suppression of the adrenal cortex by inhibiting enzymatic conversion of steroids by 3-beta-hydroxysteroid dehydrogenase/delta 5,4 ketosteroid isomerase, thus blocking synthesis of adrenal steroids. Side effect:Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin rash, and/or vomiting. Application: Trilostane can suppress cortical hormone synthesis process of 3 beta dehydrogenase, make cortisol, aldosterone synthesis reduce, clinical used in the treatment of Cushing syndrome(cortisol increase disease) and primary aldosteronism,the effect is not good than testosterone metyrapone. This product has significantly reduced blood testosterone level role, may relevant to its inhibit synthetic.
Other supplier products
All supplier products
Same products
|
|
2UUL SP01 Grip X Phone Screen Heating Separator with Suction Pad |
Seller: SHENZHEN PHONEFIX TECHNOLOGY CO.,LTD (CHINA PHONEFIX) |
Professional repair efficiency starts with precision tools.
Introducing the YCS integrated BGA... |
|
|
2UUL SP01 Grip X Phone Screen Heating Separator with Suction Pad |
Seller: SHENZHEN PHONEFIX TECHNOLOGY CO.,LTD (CHINA PHONEFIX) |
Professional repair efficiency starts with precision tools.
Introducing the YCS integrated BGA... |
|
|
Anti Insect Net |
Seller: Shandong Gold Hongye Net Co., Ltd |
Anti Insect netis suitable for plants of different sizes, indoor and outdoor gardens, and effecti... |
|
|
FT wax used in plastics: injection moulding, extrusion and pelletisation |
Seller: Syntop chemical Co.,Ltd. |
Fischer-Tropsch wax is widely used in plastics processing, particularly in industries such as inj... |
|
|
Fischer Tropsch wax used for the processing of leather care products |
Seller: Syntop chemical Co.,Ltd. |
Fischer Tropsch wax plays a significant role in the formulation of leather care products, primari... |
