Tamoxifen Citrate (Nolvadex )
Product Name:Tamoxifen Citrate(Nolvadex )
Synonyms:1-p-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene citrate;(z)-2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethylethanamine,citrate(1:;(z)-2-(para-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethylethylaminecitrate(;2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethyl-ethanamin(z)-ethanamin2-hydrox;ici46,474;kessar;noltam;tamofen
CAS:54965-24-1
MF:C32H37NO8
MW:563.64
EINECS:259-415-2
MP:140-144 °c
Storage Temp. :2-8°C
Water Solubility:slightly soluble
Chemical Properties:white to off-white powder
Biological Activity:Estrogen receptor antagonist/partial agonist. Selective and potent inhibitor of mammalian sterol isomerase. Neuroprotective in female rats in vivo . Also high affinity agonist at the membrane estrogen receptor GPR30.
Uses:For the treatment of advanced and recurrent breast cancer and ovarian cancer, etc.
Clinical Application:
1). Treatment of breast cancer.
2). Prevention of breast cancer.
3). Anti-tumor and anti-multidrug resistance.
By reducing membrane negotiability and enhancing rigidity of inter-cell binding site, Tamoxifen citrate can reduce concentration and activity of cancer metastasis promoter and various activating enzymes, so as to inhibit or hinder growth and metastasis of cancer cell. In addition, it can promote cells surrounding tumor focus to secrete a negative growth factor - transforming growth factor TGF- G, inhibiting multiply indefinitely of cancer cells; inhibiting oxidative damage of DNA bases which is caused by hydrogen peroxide generated from human neutrophils. So except for breast cancer, it is good for treatment and prevention of other malignant neoplasms, and is used for treatment of brain tumors, liver cancer, prostate cancer, etc. In addition, Tamoxifen citrate can reduce release effect of membrane P170 glycoprotein through reducing membrane negotiability, improving intracellular effective concentration of cytotoxic drug and reducing drug resistance 4).Heart protection.
Send product request
Other supplier products
 |
Testosterone Sustanon 250 | Testosterone Sustanon 250 Alias: omnadren; sustanon; omnis; testosterone blend; mixed testosterone Sustanon is mixed with testosterone Main ingr... |
 |
Tamoxifen | Tamoxifen Synonyms:(z)-2-(4-(1,2-diphenyl-1-butenyl)phenoxy)phenoxy)-n,n-dimethylethanamine;(z)-2-(para-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimet... |
 |
Vardenafil | Product Name:Vardenafil Hydrochloride Synonyms:Levitra;Valdenafil HCl;Vardenafil Hydrochloride Salt; 1-[[3-(1,4-dihydro-5-methyl-4-oxo-7-propylim... |
 |
Methyltrienolone strong anabolic steroid increase muscle | Product Name:Methyltrienolone Synonyms:Metribolone;17b-Hydroxy-17-Methylestra-4,9,11-Trien-3-One; 17a-Methyl-Trenbolone;(17S)-17-Hydroxy-17-methy... |
 |
Clomifene Citrate (Clomid) | Product Name:Clomifene Citrate (Clomid) Synonyms:Serophene;Pergotime;Clomphid;Clomid;Clomiphene Citrate;Clomiphene Citrate Salt;2-[4-(2-Chloro-1,2... |
Same products
 |
2-Amino-6-chloropurine 10310-21-1 | Seller: Xinxiang Ruicheng Technology Co.,Ltd. | 2-Amino-6-chloropurine 10310-21-1 2-Amino-6-chloropurineis a reactive purine compound used as a ... |
 |
Xanthine 69-89-6 | Seller: Xinxiang Ruicheng Technology Co.,Ltd. | Xanthine 69-89-6 Xanthineis a natural purine base that serves as a key intermediate in purine me... |
 |
Hypoxanthine 68-94-0 | Seller: Xinxiang Ruicheng Technology Co.,Ltd. | Hypoxanthine 68-94-0 Hypoxanthineis a naturally occurring purine derivative involved in nucleoti... |
 |
N,9-Diacetylguanine 3056-33-5 | Seller: Xinxiang Ruicheng Technology Co.,Ltd. | N,9-Diacetylguanine 3056-33-5 N,9-Diacetylguanine is a protected derivative of guanine designed ... |
 |
Trichlorophenylsilane | Seller: Hocon International Co., Ltd. | Trichlorophenylsilane Application Packaging and Storage Besupplied in 250Kg steel drum,Polyeth... |
