Solid Phase Peptide Synthesis
Peptide Synthesis Resins
Since Solid Phase Peptide Synthesis was first proposed by Robert Bruce Merrifield, the method of synthetic peptides became more popular than liquid phase peptide synthesis because of high efficiency. This method could assemble a peptide chain rapidly through successive reactions of amino acid derivatives on an insoluble support.
Peptide Synthesis Resins
The original peptide antibiotics are also biosynthesized and extracted from the culture of polymyxa or aeruginosa. Another synthetic method of peptides is chemical synthesis, which is divided into liquid phase chemical synthesis and solid phase chemical synthesis. The liquid phase method is mainly used for the synthesis of short peptides. The solid phase synthesis method can be used to prepare long-chain peptides, cyclic peptides, and complex. Peptide. The solid phase method is divided into a Boc method and an Fmoc method. It requires the solid phase synthesis of the carrier to achieve the growth of the peptide chain by means of stepwise amino acid condensation. The advantages of solid phase synthesis are ease of purification, shortening of the synthesis cycle, and ease of automation.
Solid phase peptide synthesis(SPPS) support consists of small, polymeric resin beads functionalized with reactive group such as amine or hydroxyl groups, which link to systhesis peptide chain step by step.
SPPS resinsis insoluble in all common solvents but swells well in most organic solvents. Better swelling degree is benefit for the reaction yields, but for short peptide easy to synthesis, lower swelling degree will be suitable and it will be good at saving solvent.
Solid phase peptide synthesis Resins are rich in variety, complete in specifications and stable in performance.
Typical Applications
Solid phase synthesis of Bivalirudin
Solid phase synthesis of Eptifibatide
Solid phase synthesis of Exenatide
Solid phase synthesis of Liraglutide
Solid phase synthesis of thymopentin
Solid phase synthesis of Thymalfasin
Solid phase synthesis of Buserelin
Solid phase synthesis of Goserelin
Solid phase synthesis of Octreotide
Solid phase synthesis of Calcitonin
Our Customized Service
We also have good experiences in research and develop the amine acid pre-loading peptide resins, and we have extended resin backbone to hydrophilic matrix, such as DEG series, TEG series, PEG series. Welcome to ask for Sunresin!
Sunresin is an innovation oriented high-tech enterprise. It is specialized in R&D, manufacturing and sales of adsorption and separation polymer resins, equipments and customized solutions including support services. As the first and the only A-share listed company resin chinaand Adsorption Resin Industry, Sunresin manufactures about 50,000 cubic meters of ion exchange and adsorption resins annually, and supplies customers with tens of adsorption and separation equipment.
Send product request
Other supplier products
 |
Peptide Synthesis Resins | Since spps Solid Phase Peptide Synthesiswas first proposed by Robert Bruce Merrifield, the method of synthetic peptides became more popular than li... |
 |
Rink Amide-MBHA Resin | 4-(2',4'-Dimethoxyphenyl-Fmoc-aminomethyl)-phenoxyacetamido-MBHA resin This resin comprises the fmoc rink amide linkerattached to rink amide mbha, ... |
 |
Enzyme Carriers 21 | SEPLITE ®Enzyme Carriers Enzyme carrier is a kind of Resin beads for Enzyme immobilization. The enzyme catalysis technology mainly relies on ... |
 |
Indicator Mixed Bed Ion Exchange Resin 21 | SEPLITE ® Indicator Mixed Bes Ion Exchange Resin Indicator Mixed Bed Ion Exchange Resin is typically cation and anion ion exchange resin all i... |
 |
Polystyrene Resin | Polystyrene Resin Bead A basic resin serves as a starting material for preparation of a wide variety of resins for combinatorial chemistry and sol... |
Same products
 |
Trimellitic anhydride 97% | Seller: Yufeng International Group Co., Ltd | Trimellitic anhydrideis a 2-benzofuran compound having oxo groups at the 1- and 3-positions and a... |
 |
Isobutyric Anhydride CAS 97-72-3 | Seller: Yufeng International Group Co., Ltd | Product Name: Isobutyric Anhydride CAS No.: 97-72-3 Purity: 99% Molecular Formula: C6H10O3 Mo... |
 |
Isobutyric Acid CAS 79-31-2 | Seller: Yufeng International Group Co., Ltd | Product Name:ISOBUTYRIC ACID Synonyms: 2-Methylpropanoic acid 79-31-2 Isobutanoic acid 2-Met... |
 |
2-Amino-2-methyl-1-propanol（AMP）CAS：124-68-5 | Seller: Yufeng International Group Co., Ltd | AtYufeng, a trusted 2-Amino-2-methyl-1-propanol Factory & Supplier, we prioritize quality and... |
 |
Dimethyl sulfoxide (DMSO) CAS: 67-68-5 | Seller: Yufeng International Group Co., Ltd | Yufengis one of the leading dimethyl sulfoxide suppliers and also a professional such manufacture... |
