Creatine Kinase-MB (CKMB)
Creatine kinase isoenzymes are an enzyme component, among which MB type is mainly present in myocardial cells. It is also a kind ofcardiac marker.
CK MB proteinis of great significance in clinical diagnosis. The serum creatine kinase level increases rapidly in various diseases, including muscular atrophy and myocardial infarction. The determination of creatine kinase activity is more reliable than electrocardiogram in the diagnosis of myocardial infarction. In myocardial infarction, creatine kinase increased within six h of onset, peaked at 24 h, and returned to normal within 3-4 days.
The isoenzyme CK-MB of creatine kinase has the highest specificity in diagnosis. Creatine kinase has attracted extensive attention and in-depth research because of its essential physiological function and clinical application value.
SEKBIOprovides related detection raw materials: Mouse anti-human CKMB mAb and Humanized anti-human CKMB mAb.
What is Creatine Kinase MB?
The creatine kinase molecule is a dimer consisting of a brain-type subunit (B) and a muscle-type subunit (M). Normal human tissues often contain three isoenzymes, which are CK-BB (CK1), CK-MB (CK2), and CK-MM (CK3) in the order of electrophoresis. CK-MB protein mainly exists in myocardial tissue, accounting for 0-4% of CK in serum. CK and CK-MB are sensitive indicators of myocardial tissue damage, especially CK-MB is more specific. The increase of creatine kinase mb antibodymainly causes the growth of CK during myocardial injury.
CK-MB Protein
Creatine kinase is one of the essential indicators of laboratory tests. When the myocardial tissue is seriously damaged, CK-MB is released into the blood, and the serum CK-MB protein becomes a vital criterion for diagnosing acute myocardial infarction.
Increased serum ck ckmbprotein is common in acute myocardial infarction, skeletal muscle injury, trauma, strenuous exercise, etc. Serum CK-MB can also be increased in malignant fever patients and some members of their families. In patients with rhabdomyosarcoma, serum CK-MB protein can be significantly increased. In addition, cardiac surgery that damages the myocardium may have a transient increase in CK-MB, which usually returns to normal within 24 hours after surgery.
Sekbioprovide creatine kinase mb test, cpk mb test, cpk mb blood test, ckmb blood test, ivd antibodyand etc. Want to more, contact us.
Send product request
Other supplier products
 |
N-terminal Pro B Type Natriuretic Peptide (NT-proBNP) | NT-proBNP is a product released under the pressure load of the heart, and its level can reflect the myocardial function and damage degree, which is... |
 |
CA242 | CA242carbohydrate antigen is a kind of saliva acidification that can be colon cancer cell lines by a series of monoclonal antibody hybridoma techno... |
 |
25-OH Vitamin D | Vitamin D is converted to 25-hydroxyvitamin D (25-OH-VD) by hydroxylation in the liver and the active 1, 25-dihydroxy vitamin D in the kidneys. ... |
 |
Recombinant COVID-19 Spike 1 His Full Length Protein | Catalog #: HP811-16 Description: Recombinant Protein, research use only Molecular weight: 29KD, theoretically Want to more about ivd raw mater... |
 |
CA19-9 | Cancer antigen 19-9 refers to a tumor marker associated with pancreatic, gallbladder, colon, and stomach cancers and is also known as an associated... |
Same products
 |
Core Drill Bits For Stone | Seller: Hebei XMF Tools Group Co., Ltd | Our Core Drill Bits for Stoneare designed for professional cutting and drilling of granite, marbl... |
 |
Uphone L181 4G Rugged PoC Radio Entry Level IP68 | Seller: Shenzhen Tianlong Century Technology Development CO., LTD | Uphone L181 4G Rugged PoC Radio Entry Level IP68 Uphone L181 4G Rugged PoC Radio – Entry-L... |
 |
Hot Melt Adhesive for Vacuum Insulation Panels | Seller: Foshan Rurga New Material Technology Co. ,Ltd | Hot Melt Adhesive for Vacuum Insulation Panels Supply & Technical Support Capabilities ... |
 |
Hot Melt Adhesive for Packaging | Seller: Foshan Rurga New Material Technology Co. ,Ltd | Hot Melt Adhesive for Packaging Bond Strength & Durability: Hot melt adhesives provide i... |
 |
Hot Melt Adhesive for Hygiene Products | Seller: Foshan Rurga New Material Technology Co. ,Ltd | Hot Melt Adhesive for Hygiene Products refers to thermoplastic pressure‑sensitive adhesives ... |
