HPMC F4M
KimaCell®HPMC F4M Hydroxypropyl methylcellulose is used as a binder and disintegrant. Low-viscosity HPMC dissolves in water to form a clear to milky white viscous colloidal solution, which can be directly used as a binder. HPMC can be used to improve the compressibility of drug particles.HPMC is a kind of non-ionic cellulose mixed ether. It is a semi-synthetic, inactive, viscoelastic polymer, often used as a lubricant in ophthalmology, or as an excipient in oral drugs.
Specification of HPMC F4M
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HPMC F4M |
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Hydroxypropyl Methyl Cellulose (HPMC) |
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Physical Analysis |
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Appearance |
White to slightly off-white fibrous or granular powder. |
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Identification A to E |
Conform |
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Solution appearance |
Conform |
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Methoxy |
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Hydroxypropoxy |
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Loss on drying |
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Residue on ignition |
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pH |
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Apparent viscosity |
3200-4800cps |
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Particle size |
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Heavy Metals |
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Heavy Metal |
≤10ppm |
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Arsenic |
≤3ppm |
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Lead |
≤3ppm |
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Mercury |
≤1ppm |
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Cadmium |
≤1ppm |
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Micro bacteria |
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Total plate count |
≤1000cfu/g |
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Yeast and Mould |
≤100cfu/g |
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Coli form |
Absent/g |
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Salmonella |
Absent/g |
Application of HPMC F4M
KimaCell® HPMC F4M is widely used in pharma industry.
Sustained-release agent: With 2-3 grams per day, the feeding amount of each 1-2G will show effect in 4-5 days.
Encapsulation: the encapsulation agent is made into an organic solvent solution or an aqueous solution for administration of tablets, especially for the prepared granules to be spray-encapsulated.
Eye drops: Since the osmotic pressure of methylcellulose aqueous solution is the same as that of tears, it is less irritating to the eyes, so it is added to eye drops as a lubricant for contacting the eyeball lens.
Jelly: as the base material of jelly-like external medicine or ointment.
Dipping medicine: as a thickener and water retention agent.
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