HPMC E3
KimaCell®HPMC E3is pharmaceutical excipient grade hydroxypropyl methyl cellulose, hypromellose, is a cellulose-based polymer for film coating, pellet granulation, and hard capsule manufacturing. Hydroxypropylmethylcellulose (HPMC) is a semi-synthetic, inert, viscoelastic polymer used as eye drops, and as a tablet coating, binder, and controlled release ingredient in oral medicines, present in many of commercial products.
Specification of HPMC E3
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HPMC E3 (9004 65 3) Hydroxypropyl Methyl Cellulose (HPMC) |
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Physical Analysis of HPMC E3 |
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Appearance |
White to slightly off-white fibrous or granular powder. |
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Identification A to E |
Conform |
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Solution appearance |
Conform |
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Methoxy |
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Hydroxypropoxy |
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Loss on drying |
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Residue on ignition |
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pH |
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Apparent viscosity |
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Particle size |
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Heavy Metals |
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Heavy Metal |
≤10ppm |
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Arsenic |
≤3ppm |
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Lead |
≤3ppm |
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Mercury |
≤1ppm |
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Cadmium |
≤1ppm |
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Micro bacteria |
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Total plate count |
≤1000cfu/g |
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Yeast and Mould |
≤100cfu/g |
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Coli form |
Absent/g |
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Salmonella |
Absent/g |
What Is HPMC E3
HPMC E3 refers to Hydroxypropyl Methylcellulose E3, which is a specific grade or type of hydroxypropyl methylcellulose. The "E3" designation typically refers to the specific grade or specification of HPMC. These designations are used to differentiate various HPMC grades based on their physical and chemical properties, including factors like molecular weight, viscosity, and other characteristics.
Application of HPMC E3
KimaCell® HPMC E3 has become one of the most widely used pharmaceutical excipients at home and abroad, because HPMC has advantages that other excipients do not have.
Water solubility
Soluble in cold water below 40°C or 70% ethanol, basically insoluble in hot water above 60°C, but can gel.
Chemical inertness
HPMC is a kind of non-ionic cellulose ether. Its solution has no ionic charge and does not interact with metal salts or ionic organic compounds. Therefore, other excipients do not react with it during the preparation process.
Stability
It is relatively stable to acid and alkali, and can be stored for a long time between pH 3 and 11 without obvious change in viscosity. The aqueous solution of HPMC has anti-mildew effect and can maintain good viscosity stability during long-term storage. The quality stability of medicines using HPMC as preparation excipients is better than that of medicines using traditional excipients (such as dextrin, starch, etc.).
Adjustable viscosity
Different viscosity derivatives of HPMC can be mixed according to different ratios, and its viscosity can change according to certain rules, and has a good linear relationship, so it can be selected according to the demand. 2.5 Metabolism inert HPMC is not absorbed or metabolized in the body, and does not provide heat, so it is a safe pharmaceutical preparation excipient.
Security
HPMC is generally considered a non-toxic and non-irritating material.
Why Choose Kimacell HPMC E3
Kimcell is a reputable company known for its expertise in manufacturing and distributing a wide range of cellulose-based products, including Hydroxypropyl Cellulose E3, available for wholesale purchase. Kimcell stands out as a trusted source for Hydroxypropyl Cellulose E3 wholesale. Their products meet rigorous quality standards and are available in various grades and specifications, ensuring they can cater to the diverse requirements of their customers.
Kimcell can supply you with Hydroxypropyl Cellulose E3 in bulk, providing you with a dependable source of this essential ingredient. The company's unwavering commitment to product excellence, customer satisfaction, and competitive pricing makes them an ideal partner for businesses seeking reliable cellulose-based solutions.
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