Phospho-L-Tyrosine Disodium Salt in molecular and cell biology research
In molecular and cell biology research, Phospho-L-Tyrosine Disodium Salt is used to probe protein-protein interactions, particularly between phosphotyrosine-containing peptides/proteins and SH2 (Src homology 2) domain-containing proteins (e.g., Grb2, PI3K), helping elucidate molecular recognition mechanisms in signal transduction. In structural biology, it serves as a ligand in X-ray crystallography or NMR studies to determine the 3D structure of phosphotyrosine-binding proteins (e.g., phosphatases, SH2 domain proteins), providing atomic-level insights into substrate recognition. It is also applied in functional validation of phosphorylation sites: through site-directed mutagenesis, it mimics constitutive phosphorylation at specific tyrosine residues in target proteins, allowing researchers to compare the activity of wild-type vs. phosphomimetic mutants and confirm the functional significance of individual phosphorylation sites (e.g., in enzyme activation or protein localization).
Other supplier products
|
|
L-Alanyl-L-cystine Manufacturer |
Nutritional and Supplement Applications of L-Alanyl-L-cystine 1. Amino Acid Source in Functional Foods L-alanine and L-cysteine play critical roles... |
|
|
Pidotimod |
1. Basic Information Product Name: Pidotimod Aliases: Pulimo, Puleyi, Pidotimod Main Chemical Component: 3-L-pyroglutamyl-thiazolidine-4-carboxylic... |
|
|
L-Alanyl-L-cystine Wholesale Price |
Pharmaceutical and Drug Development of L-Alanyl-L-cystine Drug Intermediate or Building Block It can be used as a synthetic precursor for peptide-b... |
|
|
Phospho-L-Tyrosine Disodium Salt Wholesaler |
Storage Precautions of Phospho-L-Tyrosine Disodium SaltPrevent catalytic degradation by storing the product away from biological samples (e.g., cel... |
|
|
L-Aspartic acid monosodium salt monohydrate Supplier |
L-Aspartic acid monosodium salt monohydrate's Core Background: Structure & Fundamental PropertiesTo understand this compound, it helps to start... |
All supplier products
Same products
