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99% High Purity Pharmaceutical Raw Material L-Thyroxine / T4 for Weight Loss

Basic Informations

Product Name: L-Thyroxine
CAS: 51-48-9
MF: C15H11I4NO4
MW: 776.87
EINECS: 200-101-1
Product Categories: Amino Acids;Organics;Heterocyclic Compounds;Amino Acids &Derivatives;Intermediates &Fine Chemicals;Pharmaceuticals;Isotope Labeled Compounds;Aromatics;Isotope Labelled Compounds;SYNTHROID;Isolabel;Other APIs;Inhibitors
Mol File: 51-48-9.mol




Chemical Properties
mp 235 °C
alpha -5 º(1N NaOH:EtOH 1:2)
storage temp. 2-8°C
Water Solubility insoluble
Merck 9491
CAS DataBase Reference 51-48-9(CAS DataBase Reference)
EPA Substance Registry System L-Tyrosine, O-(4-hydroxy-3,5-diiodophenyl)- 3,5-diiodo-(51-48-9)




What is T4 ?


Thyroxine is ahormone the thyroid gland secretes into the bloodstream. Once in the bloodstream, thyroxine travels to the organs, like the liver and kidneys, where it is converted to its active form of triiodothyronine. Thyroxine plays acrucial role in heart and digestive function, metabolism, brain development, bone health and muscle control. It affects almost all of the body's systems, which means proper thyroxine levels are vital for health. This is why many doctors will test T4 levels along with the more common T3 levels when testing for thyroid disorders.

Having too little thyroxine or too much thyroxine can cause health problems. If your body releases too much thyroxine, you will suffer acondition called thyrotoxicosis. This can cause agoiter, which is aswelling of the neck because of an enlarged thyroid gland. Thyrotoxicosis can also cause menstrual irregularities, an increase in bowel movements, weight loss, heat intolerance, fatigue and irritability. Thyrotoxicosis is commonly caused by hyperthyroidism, tumors in the thyroid gland or thyroid inflammation.
The body can also produce too little thyroxine, acondition known as hypothyroidism. Low thyroxine levels cause problems with development if it occurs when an individual is young. In adults, thyroxine deficiency will lower the metabolic rate, causing weight gain, memory problems, infertility, fatigue and muscle stiffness.



Function


The thyronines act on nearly every cell in the body. They act to increase the basal metabolic rate, affect protein synthesis, help regulate long bone growth and neural maturation, and increase the body's sensitivity to catecholamines by permissiveness. The thyroid hormones are essential to proper development and differentiation of all cells of the human body. These hormones also regulate protein, fat, and carbohydrate metabolism, affecting how human cells use energetic compounds. They also stimulate vitamin metabolism. Numerous physiological and pathological stimuli influence thyroid hormone synthesis.

Thyroid hormone leads to heat generation in humans. However, the thyronamines function via some unknown mechanism to inhibit neuronal activity; this plays an important role in the hibernation cycles of mammals and the moulting behaviour of birds. One effect of administering the thyronamines is asevere drop in body temperature.







Applications

Levothyroxine is typically used to treat hypothyroidism,and is the treatment of choice for patients with hypothyroidism, who often require lifelong thyroid hormone therapy.It may also be used to treat goiter via its ability to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing.Levothyroxine is also used as interventional therapy in patients with nodular thyroid disease or thyroid cancer to suppress thyroid-stimulating hormone (TSH) secretion.



COA

Item Specification Result
Appearance An odorless, almost white or buff colored powder pass
Solubility 1,Very slightly soluble in water pass
2,slightly soluble in alcohol pass
3,practically insoluble in most other organic solvents pass
4,disolves in diluted aqueous sodium hydroxide solutions Pass
Identification a) Heat about 50 mg with afew drops of sulfuric acid in aporcelain crucible: violet vapors of iodine are evolved. pass
b)The retention time of the major peak is confirm to the RS pass
Loss on Drying Not more than 4.0% 0.46%
[a]20/D
C=1 in 1M HCl/EtOH 1:4
+18 ~+22o +20.9o
Assay(HPLC) Not less than 95.0% 99.18%
Levothyroxine sodium Not more than 5.0% 0.68%
Conclusion: Up to the Standard for Export




Why choose us?

1.Good quality.All products are produced under GMP conditions according to Standard Operation Procedure(SOP), not from little underground labs or black markets, so the quality is guaranteed.

2.Discreet packing methods.For your safety and to insure delivery all products will be packed in adiscreet way to prevent any suspicions, no steroids related name will appear on the parcels.

3.99.99% customs clearance rate.We have rich experience in shipping parcel to USA, Australia, UK, Canada, Brazil, Russia, Germany, Poland, Mexico, etc.

4.Injectable steroid.We offer melting powder into liquid service.And ship the liquid in special bottles.







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Order Guide

Q1: Have your Product Quality been Approved by Third Party Lab?
A: Yes, All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. So you will be assured with Good Quality if you choose us.

Q2:How do you treat quality complaint?
A:First of all, our QC department will do strict examination of our export products by HPLC, UV, GC ,
TLC and so on in order to reduce the quality problem to near zero. If there is areal quality problem ,caused by us, we will send you free goods for replacement or refund your loss.

Q3: Is there any discount?
A: Yes, for larger quantity, we always support with better price.

Q4:How long does it take to the goods arrived ?
A:It is Depending on your location,
For small order, please expect 5-7 days by DHL,UPS,TNT, FEDEX, EMS.
For mass order, please allow 5-8 days by Air, 20-35 days by Sea.

Q5Doyouhaveanyreshipmentpolicy ?
we have good after-sale service and re-shipment policy if the parcellose
Our long association withour clients has brought great benefits
We always take the upmost care in the packaging of our products
our clients will confirm this as even they struggle to find them without help at times.
But in spite of our best efforts it is still possiblewill seize asmall number of packages.
In this circumstance we promise reship freeto establishlong term relationship

Q6 :Can Iget asample?
A: Of course. For most products we can provide you afree sample, while the shipping cost should
undertake by your side.

we are aleading manufacturer of steroid raw materials,.and Peptides
many distributors and labs ,bodybuilders from worldwide cooperate with us ,
all speak highly of our safe shipping and goods .
If you require further information please donot hesitate to contact us.




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