9H-Purin-6-amine,9-b-D-arabinofuranosyl-2-fluoro-
Classification:PharmaceuticalsandBiochemicals
CasNO.:21679-14-1
MolecularFormula:C10H12FN5O4
MeltingPoint:265-268°C
BoilingPoint:747.3°Cat760mmHg
Stability:null
Refractiveindex:1.876
FlashPoint:405.8°C
Purity:99%
Appearance:whitesolid
usage:APIsPharmaceuticalAdjuvantBiochemicals&Biotechproducts
BrandName:ROYAL
EINECS:244-525-5
Aliase:9H-Purin-6-amine,9-b-D-arabinofuranosyl-2-fluoro-
Purity:99%
Appearance:WHITE
Brand:ROYAL
quality:highquality
Usage:
Usedasanantineoplastic
Packaging&Delivery
PackagingDetail:25KG/DRUM
DeliveryDetail:SEE,AIR,EXPRESS
DetailedDescription
APIsPharmaceuticalAdjuvantBiochemicals&Biotechproducts
Name:
9H-Purin-6-amine,9-b-D-arabinofuranosyl-2-fluoro-(RelatedReference)
EINECS:
244-525-5
MolecularFormula:
C10H12FN5O4
CASRegistryNumber:
21679-14-1
Synonyms:
Adenine,9-b-D-arabinofuranosyl-2-fluoro-(8CI);2-FluoroAra-A;2-Fluoro-9-b-D-arabinofuranosyladenine;2-Fluoroadeninearabinoside;9-b-D-Arabinofuranosyl-2-fluoroadenine;9-b-D-Arabinosyl-2-fluoroadenine;F-ara-A;NSC118218;NSC118218H;FludarabineBase;
Appearance:
whitesolid
MolecularWeight:
285.23
Density:
2.17g/cm3
BoilingPoint:
747.3°Cat760mmHg
MeltingPoint:
265-268°C
FlashPoint:
405.8°C
StorageTemperature:
2-8°C
Refractiveindex:
1.876
Solubility:
Verysoluble
BiologicalActivity:
PurineanalogthatinhibitsDNAsynthesis.Exhibitsantiproliferativeactivity(IC50=1.54μMinRPMIcells)andtriggersapoptosisthroughincreasingBaxanddecreasingBid,XIAPandsurvivinexpression.Displaysanticanceractivityagainsthematologicalmalignanciesinvivo.
Usage:
Usedasanantineoplastic
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