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Citicholine

Product name:Citicholine Other name:Cytidine 5'-diphosphocholine,Citicoline Base,CDP-Choline,CDP Choline,CDPC CAS Number:987-78-0 Molecular Formula:C14H26N4O11P2 Molecular Weight:488.3 Purity:99% Appearance:White solid powder Package:25kg/drum Usage:nootropics What is Citicholine? Citicoline is a nutrient actually found in the body in addition to being a nutritional supplement.It is a water soluble compound that is an essential intermediary in the synthesis of phosphatidylcholine, which is a major component of grey matter brain tissue. It also helps to create a number of other types of phospholipids, which are essential components in cell membranes. This supplement was first developed in Japan, and was used to help people who had suffered a specific type of stroke to better recover. It was also noted that this supplement has shown promise for helping patients who are suffering from glaucoma. It appears capable of nourishing nerves as well as improving blood circulation within the brain. How does it work? The primary mechanism of action for Citicoline is as a source of Choline. Choline is a nutrient similar to the B Vitamins that is necessary for the brain to be able to make the Acetylcholine neurotransmitter.However, the vast majority of the population does not get the recommended amount of choline form their diet which can lead to mental impairment even with minor deficiencies. Citicoline can help to supplement the amount of choline in your bloodstream which them promotes greater Acetylcholine production.citicoline What is most interesting about Citicoline is that it has proven more effective at increasing brainpower than taking equivalent amounts of choline supplements. This is because Citicoline is actually more bioavailable and a closer precursor to Acetylcholine. After taking a Citicoline dosage, this compound is absorbed into the bloodstream fairly quickly and then crosses the blood-brain barrier, reaching the brain. The two main components of the supplement, cytidine and choline, are broken down and then widely distributed. As it becomes incorporated into phospholipids it helps to activate their continued biosynthesis. A number of different neurotransmitters and brain chemicals are also affected by Citicoline. It acts as a precursor to Acetylcholine and helps to influence a number of cognitive processes through this action.Dopamine and Norepinephrine levels are also increased throughout the central nervous system. This may also be why many users report their overall stress levels decrease and a feeling of general well-being to be improved while using this supplement. Description: Citicoline also known as cytidine diphosphate-choline (CDP-Choline) or cytidine 5'-diphosphocholine is nootropic. It is an intermediate in the generation of phosphatidylcholine from choline. Studies suggest that CDP-choline supplements increase dopamine receptor densities, and suggest that CDP-choline supplementation helps prevent memory impairment resulting from poor environmental conditions. Preliminary research has found that citicoline supplements help improve focus and mental energy and may possibly be useful in the treatment of attention deficit disorder. Citicoline has also been shown to elevate ACTH independently from CRH levels and to amplify the release of other HPA axis hormones such as LH, FSH, GH and TSH in response to hypothalamic releasing factors. These effects on HPA hormone levels may be beneficial for some individuals but may have undesirable effects in those with medical conditions featuring ACTH or cortisol hypersecretion including PCOS, type II diabetes and major depressive disorder.



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