If you are going to consult the information about from one of the leading manufacturers and suppliers in China,Website:, Biopharmaleader Co.,Ltd is always at your service.Product InformationCAS NO. Product NameSonidegibSynonymsErismodegib;LDE225FormulaC26H26F3N3O3Molecular Weight485.49Spec / Purity98%minSupply CapacityDetailsSonidegib (erismodegib or LDE225) is a Hedgehog signaling pathway inhibitor being developed as an anticancer agent. It has been investigated as a potential treatment for pancreatic cancer,breast cancer,basal cell carcinoma of the skin,small cell lung cancer,medulloblastoma,advanced solid tumours (including ovarian, breast, pancreatic, stomach, oesophageal cancers and glioblastoma multiforme),acute leukaemia,chronic myeloid leukaemia,myelofibrosis and essential thrombocythaemia .It has demonstrated significant efficacy against melanoma in vitro and in vivo. It also demonstrated efficacy in a mouse model of pancreatic cancer.
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