Mannitol
Synonyms: DL-Mannitol; Hexahydroxyhexane CAS: 69-65-8 EINECS: 200-711-8 Assay: 99% min.Standard: BP/EP/USP Packing: 25kg/cardboard drumCharacter: Colorless to white needle-like or rhombic columnar crystals or crystalline powder. Odorless, has a cool sweet taste. Sweetness of sucrose about 57% to 72%. 8.37J per g of heat generated is about half glucose.Containing a small amount of sorbitol. The relative density of 1.49. Specific rotation [α] D20-0.40 ° (10% aqueous solution). Minimal moisture absorption. Solution stability. Of acid, dilute alkali stable. Oxidation by oxygen in air does not. Soluble in water (5.6g/100ml, 20 ℃) and glycerol (5.5g/100m1). Slightly soluble in ethanol (1.2g/100m1). Soluble in hot ethanol. Almost insoluble in most other common organic solvents. 20% aqueous solution of pH 5.5 to 6.5.Usage: Mannitol in medicine is a good diuretic to reduce intracranial pressure, intraocular pressure and renal pharmaceuticals, dehydration, sugar substitutes, also used as tablet excipients and solid, liquid diluent. Mannitol injection as a high penetration of antihypertensive pharmaceuticals, the clinical brain disorders, especially rescue the rescue of a pharmaceutical commonly used, to reduce intracranial pressure with antihypertensive pharmaceuticals require rapid, effective and accurate.Used as a tablet excipient, mannitol no moisture absorption, fast drying, good chemical stability, but also has tasty, and good granulation Characters for anti-cancer pharmaceuticals, antibiotics, antihistamines, and vitamins and other large part of the tablet. In addition, pharmaceuticals used to sober up, mouth refreshing agent Chewable agentFood additive, low-calorie sweetener; gum and candy anti-stick; nutritional supplement agents and tissue conditioner; moisturizer; filler.the goods in the sugar and sugar alcohols in the minimum water absorption, and sweet with a refreshing, for maltose, chewing gum, cakes and other foods of anti-sticking, and as a general anti-sticking pastry flour. Diabetes can also be used with food, fitness and food low calorific value, low-sugar sweetener.In industry, mannitol can be used for the plastics industry, the system glycerol rosin esters and synthetic resins, explosives, detonators (nitrification mannitol) and so on. In the chemical analysis for the determination of boron in biological testing for bacterial culture on the agent. Although mannitol can be absorbed by the gastrointestinal, but does not accumulate in the body. Is absorbed, is metabolized in the body part, other part in the urine; by hydrobromic acid can be obtained dibromo mannitol.Reagents for the analysis, but also for synthetic resins and medicine
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