Ipamorelin Popular Bodybuilding Peptide Supplier-Polypeptide.ltd
1. What is Ipamorelin?
A pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) and a ghrelin mimetic with growth hormone (GH) releasing activity. Ipamorelin mimics ghrelin and binds to the ghrelin receptor (or GH secretagogue receptor, GHSR) in the brain, thereby selectively stimulating the release of GH from the pituitary gland. This results in increased plasma GH levels, which would affect many biological processes. Besides its presence in the brain, GHSR can also be found in the gastrointestinal tract, heart, lung, liver, kidney, pancreas, adipose tissue, and immune cells.
2. What is the main benefit of Ipamorelin?
Evidence suggests that growth hormone (GH) and growth hormone secretagogues, such as ipamorelin, may help reduce the catabolic effects of glucocorticoids on muscle. Studies conducted on rats treated with glucocorticoids have shown a decrease in nitrogen wasting in the liver and an improved nitrogen balance after ipamorelin administration.
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