Lab Supply High Quality Follistatin 344 1mg/Vials

Lab Supply High Quality Follistatin 344 1mg/Vials


Basic info.

Product: Follistatin 344 / Unit Size: 1 mg/vial
CAS NO. 80449-31-6
Molecular Formula: C13H16O3
Appearance: White Powder
Synonyms: Follistatin 344 , Follistatin
Country of manufacture: China

Description:

Follistatin is fascinating protein that can increase muscle mass beyond natural potential by suppressing myostatin. Scientists first identified follistatin while examining porcine (re: pig) follicular fluid in the ovaries.

Follistatin is naturally found in the skeletal muscle of almost all mammals with advanced or developed characteristics, such as humans, rodents, and cows. Follistatin is high in the
non-essential amino acid cystine but unlike most proteins discussed in the fitness world, follistatin has carbohydrates attached to it.

Follistatin, specifically Follistatin 344 (FS344), quickly gained popularity in the bodybuilding community as a potential supplement to rapidly increase lean tissue mass. Another protein, follistatin-related gene (FLRG) acts on similar pathways as FS344 regarding its muscle building properties. Increased lean tissue mass could give a bodybuilder an advantage in a competitive setting and be the differentiating factor between first and second place.

Follistatin (FS) was initially identified as a follicle-stimulating hormone inhibiting substance found in ovarian follicular fluid. FS is a high-affinity activin-binding protein that can act as an activin antagonist. Two alternatively spliced follistatin mRNAs exist, encoding mature FS with 288 amino acid (aa) residues (FS-288) and 315 aa residues (FS-315). Natural FS purified from porcine ovaries is primarily a carboxy-terminal truncated form of FS-315 composed of 300 aa residues.

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. Follistatin binds directly to activin and functions as an activin antagonist. specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (fsh).

Application:

Follistatin (FST) is a secreted glycoprotein that was first identified as a follicle stimulating hormone inhibiting substance in ovarian follicular fluid (1, 2). Human Follistatin cDNA encodes a 344 amino acid (aa) protein with a 29 aa signal sequence, an Nterminal atypical TGF binding domain, three Follistatin domains that contain EGFlike and kazallike motifs, and a highly acidic Cterminal tail. Follistatin is a secreted protein that binds to ligands of the TGF-Beta family and regulates their activity by inhibiting their access to signaling receptors. It was originally discovered as activin antagonists whose activity suppresses expression and secretion of the pituitary hormone FSH (follicle stimulating hormone). In addition to being a natural antagonist, follistatin can inhibit the activity of other TGF-Beta ligands including BMP-2, -4, -6, -7, Myostatin, GDF-11, and TGF-Beta1. Follistatin is expressed in the pituitary, ovaries, decidual cells of the endometrium, and in some other tissues. Recombinant human Follistatin is a 37.8 kDa protein containing 344 amino acids .

Follistatin and Muscle Growth:

Follistatin works by binding to and inhibiting transforming growth factor- (TGF-) peptides such as myostatin which is responsible for regulating and limiting muscle growth. It's also worth pointing out that myostatin may have a regulatory role in skeletal muscle fibrosis; too much myostatin can impair tissue function and cause chronic disease in vital organs, tissues, and bone marrow.
In additional to suppressing the degenerative properties of myostatin, follistatin also suppresses the pituitary gland synthesis and secretion of follicle-stimulating hormone (FSH). [1] High FSH levels in men may indicate that testicles are not functioning correctly; this condition limits muscle growth, recovery, and normal hormonal function.However, FSH levels that are too low can also negatively impact health and reproductive capabilities.



Shipping & Delivery
1.Packages are generally dispatched within approximately 2 days after receipt of payment.
2.After the each shipping we will provide you with:
1) a link & tracking number to track your package online.
2) the few pictures with your order & details.
3.About the Custom clearance,we packed in disguise ways.In our experience,the appropriate and safe delivery,there won't be problems.
4.We confirm 99% clearance,100% resending.
5.Is it the best & safest shipping for all our repeat customers!


Packing Details
Discreet packing ways as your requirement, 100% go through.

Storage
Store in cool and dry area and keep away from direct sunlight.oC

Shelf life
2 years, keep in formal storage condition.

MOQ
We accept any Qty you require, grams to kilograms.
Samples Available, Contact now!

Top reason why you choose us ?
(1)Fast discreet delivery with great shipping success!
(2)Pictures with your order & details!
(3)We will provide you the tracking number!
(4)Keep track of your goods untill the goods are sent in to your hands.
(5)We confirm 99% clearance,100% resending.
(6)High quality,100% pure products!
(7)Delivery time approx.4-6 business days.
(8)Best, Safe and Secure services.
(9)Customer support 24/7.


Order infos
Payment Methods:West Union,Moeny Gram, Bitcoin and Bank Transfer.
Delivery Ways:EMS,HKEMS,TNT,DHL,FedEX,UPS etc.
Shipment Time:Within 12 hours after confirmation of your payment
Other Service:Safe shipment,high purity and best price for you.





Send product request

To: Guangzhou Kafen Biotech Co.,Ltd
Your E-mail:
Message text:


Send to other suppliers

Other supplier products

Tmt Blend 500 Semimade Steroid Solution Tmt Blend500
Tmt Blend 500 Semimade Steroid Solution Tmt Blend500 Tmt Blend 500 Semimade Steroid Solution Tmt Blend500 Basic info. Each 1ml TMT Blend 500 semimade steroid solution contained: Trenbolone Enanthat...
Hormone Cjc-1295 Without Dac
Hormone Cjc-1295 Without Dac Hormone Cjc-1295 Without Dac Basic info. CJC 1295 Assay:99.20% CAS No.:863288-34-0 Usage: Helps Injury Recovery Times Export Markets: Global Pac...
Pharmaceutical Grade Hydroxypropyl-Beta-Cyclodextrin with High Reputation
Pharmaceutical Grade Hydroxypropyl-Beta-Cyclodextrin with High Reputation Pharmaceutical Grade Hydroxypropyl-Beta-Cyclodextrin with High Reputation Basic info. CAS No.: 128446-35-5 Other Names: 2-HP-BETA-CD,2hpbcd MF: ...
Pharmaceutical USP37 Pregabalin with Competitive Price
Pharmaceutical USP37 Pregabalin with Competitive Price Pharmaceutical USP37 Pregabalin with Competitive Price Basic info. Pregabalin CAS: 148553-50-8 MF: C8H17NO2 MW: 159.23 Assay: 99% Appearance: Wh...
17 Alpha Hydroxyprogesterone for Cancer Treatment 68-96-2
17 Alpha Hydroxyprogesterone for Cancer Treatment 68-96-2 17 Alpha Hydroxyprogesterone for Cancer Treatment 68-96-2 Basic info. Product Name:17 Alpha Hydroxyprogesterone Chemical name: 17-alpha-hydroxyp...
All supplier products

Same products

china car parts factory Wholesale high quality ceramic/semi metal NISSAN SUZUKI Brake pads oem 41060-zp025
china car parts factory Wholesale high quality ceramic/semi metal NISSAN SUZUKI Brake pads oem 41060-zp025 Seller: yxdel Yxdel car parts
glass soap pump jar
glass soap pump jar Seller: shandong boshan jingyuan glass handicraft co,. ltd.
Laser Cut Ventilation Hole in Sportswear
Laser Cut Ventilation Hole in Sportswear Seller: Unikonex Technologies Co., Ltd. The advantage of laser cut ventilation hole is the sealing and fabric reinforcement that occurs a...
2FDCK 2-FDCK kari@jx-skill.com Free Sample
2FDCK 2-FDCK kari@jx-skill.com Free Sample Seller: Appearance: crystal Application: medical treatment DeliveryTime: Spot supply PackAge: Jinbo wi...
2F-A-PVP 2F-APVP kari@jx-skill.com High Quality
2F-A-PVP 2F-APVP kari@jx-skill.com High Quality Seller: Appearance: crystal Application: medical treatment DeliveryTime: Spot supply PackAge: Jinbo wi...