.

Eptifibatide

Product Name

Eptifibatide;

Sequence

Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2

Cas No.

Molecular Formula

C35H49N11O9S2

Molecular Weight

832.4

Appearance

White slightly yellwish powder

Specific Rotation[20/D]

-75.0~-95.0°(C=1,1%HAc)

Amino Acids composition

± 10%

Peptide Purity (By HPLC)

≥98% by area integration

Related Substance (By HPLC)

Total Impurities (%)≤2.0% Largest Single Impurity (%)≤ 1.0%

Water Content (Karl Fischer)

≤8.0%

Peptide Content(N determination)

≥80%

Acetate Content

≤15%

IR spectrum

in accordance

Brief introduction:

Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class.[1] Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri).

It belongs to the class of the so-called arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market.

Indications

Eptifibatide is used to reduce the risk of acute cardiac ischemic events (death and/or myocardial infarction) in patients with unstable angina or non-ST-segment-elevation (e.g., non-Q-wave) myocardial infarction (i.e., non-ST-segment elevation acute coronary syndromes) both in patients who are to receive non surgery (conservative) medical treatment and those undergoing percutaneous coronary intervention (PCI).

The drug is usually applied together with aspirin or clopidogrel and (low molecular weight or unfractionated) heparin. Additionally, the usual supportive treatment consisting of applications of nitrates, beta-blockers, opioid analgesics and/or benzodiazepines should be employed as indicated. Angiographic evaluation and other intensive diagnostic procedures may be considered a first line task before initiating therapy with eptifibatide.


Отправить запрос, связаться с поставщиком

Кому: 122150
Ваш E-mail:
Текст письма:


Send to other suppliers

Другие товары поставщика

Boldenone Undecylenate
Boldenone Undecylenate Boldenone Undecylenate CAS NO.: 13103-34-9 Molecular Formula: C30H44O3 Molecular weight: 452.67 Assay: 97.0~103.0% Standard: Enterprise Standard B...
Trenbolone Ace 10161-34-9 Finaplix / Revalor-H Powder Muscle Building Bulking Steroids
Trenbolone Ace 10161-34-9 Finaplix / Revalor-H Powder Muscle Building Bulking Steroids Basic Info Model NO.:315-37-7 CAS No.:315-37-7 Purity:98%Testosterone Enantate Molecular Weight:400.6 Trademark:Saichuang Origin:China Syno...
5949-44-0 Testosterone Undecanoate (Andriol)
5949-44-0 Testosterone Undecanoate (Andriol) Basic Info Model NO.:5949-44-0 Synonyms:Andriol Other Name:Andriol, Test Undecanoate Einecs:227-712-6 Other:Test Undecanoate Trademark:saichuan...
Bivalirudin Trifluoroacetate
Bivalirudin Trifluoroacetate Product Name Bivalirudin Trifluoroacetate Sequence D-Phe-Pro-Arg-Pro-Gly-Gly-Gly-Gly-Asn-Gly-Asp-Phe-Glu-Glu-Ile-Pro-Glu-Glu-Tyr-Leu-OH...
99% Purity Hot Sale Ananbolic Steroid Hormone Powder Trenbolone Acetate
99% Purity Hot Sale Ananbolic Steroid Hormone Powder Trenbolone Acetate Basic Info Model NO.:10161-34-9 Trenbolone Acetate CAS:10161-34-9 Trenbolone Acetate Mf:C20h24o3 Trenbolone Acetate Purity:99% Trenbolone Aceta...
Все товары поставщика

Похожие товары

Micronized polypropylene wax for injection moulding
Micronized polypropylene wax for injection moulding Продавец: Syntop chemical Co.,Ltd. The incorporation of polypropylene micronized wax into injection moulding processes delivers the ...
Drum Type Mobile Mixing Station
Drum Type Mobile Mixing Station Продавец: Yousheng Machinery Equipment Co.,Ltd Drum Type Mobile Mixing Station Drum Type Mobile Mixing StationPortable Drum Concrete Batch Plan...
Washable Cheap 13.56Mhz 213 Nfc Mini Stickers 13.56 Mhz RFID Label Sticker Tag HF/UHF Tags Dry Inlay
Washable Cheap 13.56Mhz 213 Nfc Mini Stickers 13.56 Mhz RFID Label Sticker Tag HF/UHF Tags Dry Inlay Продавец: XIUCHENG RFID Size:On request Material:PET, PVC,paper or customized Frequency:UHF/HF Printing:Thermal transf...
Micronized wax used for industrial paint processing
Micronized wax used for industrial paint processing Продавец: Syntop chemical Co.,Ltd. Micronized wax is a vital functional additive in industrial paint processing, with primary functi...
Plant Growth Regulator Manufacturer
Plant Growth Regulator Manufacturer Продавец: HEBEI LAIKE BIOTECH CO.LTD Plant Growth Regulator Manufacturer Plant Growth Regulator Manufacturer - Laike Biotech spec...