Eptifibatide
|
Product Name |
Eptifibatide; |
|
Sequence |
Mpr-Har-Gly-Asp-Trp-Pro-Cys-NH2 |
|
Cas No. |
|
|
Molecular Formula |
C35H49N11O9S2 |
|
Molecular Weight |
832.4 |
|
Appearance |
White slightly yellwish powder |
|
Specific Rotation[20/D] |
-75.0～-95.0°（C=1，1%HAc） |
|
Amino Acids composition |
± 10% |
|
Peptide Purity (By HPLC) |
≥98% by area integration |
|
Related Substance (By HPLC) |
Total Impurities (%)≤2.0% Largest Single Impurity (%)≤ 1.0% |
|
Water Content (Karl Fischer) |
≤8.0% |
|
Peptide Content(N determination) |
≥80% |
|
Acetate Content |
≤15% |
|
IR spectrum |
in accordance |
Brief introduction:
Eptifibatide (Integrilin, Millennium Pharmaceuticals, also co-promoted by Schering-Plough/Essex), is an antiplatelet drug of the glycoprotein IIb/IIIa inhibitor class.[1] Eptifibatide is a cyclic heptapeptide derived from a protein found in the venom of the southeastern pygmy rattlesnake (Sistrurus miliarius barbouri).
It belongs to the class of the so-called arginin-glycin-aspartat-mimetics and reversibly binds to platelets. Eptifibatide has a short half-life. The drug is the third inhibitor of GPIIb/IIIa that has found broad acceptance after the specific antibody abciximab and the non-peptide tirofiban entered the global market.
Indications
Eptifibatide is used to reduce the risk of acute cardiac ischemic events (death and/or myocardial infarction) in patients with unstable angina or non-ST-segment-elevation (e.g., non-Q-wave) myocardial infarction (i.e., non-ST-segment elevation acute coronary syndromes) both in patients who are to receive non surgery (conservative) medical treatment and those undergoing percutaneous coronary intervention (PCI).
The drug is usually applied together with aspirin or clopidogrel and (low molecular weight or unfractionated) heparin. Additionally, the usual supportive treatment consisting of applications of nitrates, beta-blockers, opioid analgesics and/or benzodiazepines should be employed as indicated. Angiographic evaluation and other intensive diagnostic procedures may be considered a first line task before initiating therapy with eptifibatide.
在线联系供应商
Other supplier products
 |
99% Purity Steroid Powder Testosterone Enanthate for Bodybuilding | Basic Info Model NO.:315-37-7 Customized:Customized Suitable for:Adult Purity:>99% Alias:Primoteston Depot Testosterone Enanthate CAS:315-37-... |
 |
Dexamethasone-21-Acetate | Detail Dexamethasone-21-Acetate Chemical Name: Dexamethasone-17-acetate CAS: 1177-87-3 Molecular formula: C24H31FO6 MW: 434.5 Packing: ... |
 |
Trenbolone Ace 10161-34-9 Finaplix / Revalor-H Powder Muscle Building Bulking Steroids | Basic Info Model NO.:315-37-7 CAS No.:315-37-7 Purity:98%Testosterone Enantate Molecular Weight:400.6 Trademark:Saichuang Origin:China Syno... |
 |
100mg/Ml Injectable Trenbolone Enanthate, Trenbolone E, Tren Enanthate | Basic Info Model NO.:Trenbolone Enanthate Trenbolone E, Tren Enanthate Tren Enanthate:Injectable Tren Enanthate Trademark:Yuancheng Saichuang O... |
 |
Sildenafil Mesylate | Sildenafil Mesylate CAS: Molecular Formula: C22H30B6O4S. CH3SO3H Molecular Weight: 570 Appearance: white to almost white crystalline ... |
Same products
 |
C500-1.7 Series High Flow Multi-Stage Centrifugal Blower /Centrifugal Blower | 卖方: Greentech International (Zhangqiu) Co., Ltd | Greentech International (Zhangqiu) Co., Ltdis the professional blower supplier.Multistage Centrif... |
 |
Common Rail injector control valve F00VC01303 | 卖方: China Lutong Part Plant | Common Rail injector control valve F00VC01303 Tina#Stainless Steel Cylindrical Pin##Denso Common... |
 |
Common Rail injector control valve F00VC01200 | 卖方: China Lutong Part Plant | Common Rail injector control valve F00VC01200 Tina#Stainless Steel Cylindrical Pin##Denso Common... |
 |
Injector Control Valve Plate 24# | 卖方: China Lutong Part Plant | Injector Control Valve Plate 24# Tina#Stainless Steel Cylindrical Pin##Denso Common Rail Injecto... |
 |
Injector Control Valve Plate 12# | 卖方: China Lutong Part Plant | Injector Control Valve Plate 12# Tina#Stainless Steel Cylindrical Pin##Denso Common Rail Injecto... |
