SiSiB® PC9210
Hexamethyldisilazane
SiSiB® PC9210 (also called as Bis trimethylsilyl amine; HMDS chemical; HMDZ) is an extremely versatile and strong silylating agent. It is primarily used for the protection of sensitive functional groups during chemical synthesis.
Trimethylsilyl moiety silazane is a versatile blocking agent employed in chemical synthesis. Introduction of silyl protective groups has following advantages.
Masking of reactive functional groups.
Improvement of solubility in polar and or non polar solvent.
Improved product stability.
Easy removal of protective groups .
Additional activation of reactive centres.
Easyelimination of hydrogen bonds.
One of the advantages of SiSiB® PC9210 over other hexa methyl di silazaneis that no base is needed as a hydrochloric acid acceptor. SiSiB® PC9210 produces ammonia which escapes easily from the reaction mixture during silylation.
For the price of HMDS/HMDZ chemical and other relevant information, please feel free to contact us.
Technical Data
CAS No. |
999 97 3 |
EINECS No. |
213-668-5 |
Formula |
C6H19NSi2 |
Molecular Weight |
|
Boiling Point |
125°C |
Flash Point |
15°C |
Ignition point |
325°C |
Color and Appearance |
Clear colorless liquid |
Density25/25°C |
|
Refractive Index |
|
Application
SiSiB® PC9210 hmds hexamethyldisilazanesilylating agent can be used to introduce trimethylsilyl group into organic molecules containing an active hydrogen atom such as alcohols, carboxylic acids, amines etc. The most common industrial SiSiB® PC9210 hexamethyldisilazane applicationsis in production of semi synthetic beta lactum antibiotics as ampicillin and cephalexin.
The usual procedure is to protect the carboxylic group in the antibiotic with HDMS followed by acylation with the desired acylchloride. Finally, desilylation under mild aqueous conditions gives the desired product.
Packing and Storage
SiSiB® PC9210 is supplied in 150Kg steel drum.
In the unopened original container SiSiB® PC9210 has a shelf life of one year in a dry and cool place.
For more information about hexamethyldisilazane uses, please feel free to contact us!
SiSiBSILICONES,as an excellent silicone supplier, offers a wide range of custom silicone productsfor you to choose from.
Отправить запрос, связаться с поставщиком
Другие товары поставщика
Hydroxy Silicone Fluids | Silanol Silicone Oil, Silanol Silicone Fluid, Reactive Hydroxy Silicone, Hydropropyl Silicone Fluid, Hydroxy Silicone Oil SiSiB is a leading manuf... | |
Silicone Textile Softener | Since our establishment as a silicone softenersmanufacturer in 1989, silicone has been our core business, especially custom food and medical grade ... | |
SiSiB® PC6122 1,2-Bis(triethoxysilyl)ethane | SiSiB® PC6122 1 2 Bis triethoxysilyl ethane SiSiB® PC6112 (BTMSE) and SiSiB® PC6122 (BTSE) are clear to straw bis-silanes. SiSiB&r... | |
SiSiB® PC5620 Triethylchlorosilane | SiSiB® PC5620 Triethylchlorosilane SiSiB® PC5620 is a clear, colourless to yellowish, pungent smelling, caustic and flammable liquid. I... | |
SiSiB® PC5420 Tetraethoxysilane | SiSiB® PC5420, the ethyl ester of orthosilicic acid, is a colorless, low-viscosity liquid with an SiO2 content of 28.5%. It is also called as T... |
Похожие товары
SiSiB® PC9210 | Продавец: Nanjing SiSiB Silicones Co., Ltd | Hexamethyldisilazane SiSiB® PC9210 (also called as Bis trimethylsilyl amine; HMDS chemical; ... | |
Endoscopic Retriever Bag | Продавец: Victor Medical Instruments Co., Ltd. | Usage of Endoscopic Retriever Bag Instruction for Use The single use endopouch retrieval bagi... | |
Shank Adapter HC | Продавец: Litian Heavy Industry Machinery Co., Ltd | Litian shank adapters use high-quality alloy structural steel, and adopt a complete set of mature... | |
Smart 32 Nucleic Acid Extraction Instrument | Продавец: Daan Gene Co., Ltd. | Smart 32 is a nucleic acid extraction instrumentadopting magnetic bead technology. Combined with ... | |
Neisseria gonorrhoeae Fluorescent Polymerase Chain Reaction Diagnostic Kit | Продавец: Daan Gene Co., Ltd. | Gonorrhoeae, caused by Neisseria gonorrhoeae, is the second most common bacterial STI and results... |