.

SiSiB® PC9210

Hexamethyldisilazane

SiSiB® PC9210 (also called as Bis trimethylsilyl amine; HMDS chemical; HMDZ) is an extremely versatile and strong silylating agent. It is primarily used for the protection of sensitive functional groups during chemical synthesis.

Trimethylsilyl moiety silazane is a versatile blocking agent employed in chemical synthesis. Introduction of silyl protective groups has following advantages.

Masking of reactive functional groups.

Improvement of solubility in polar and or non polar solvent.

Improved product stability.

Easy removal of protective groups .

Additional activation of reactive centres.

Easyelimination of hydrogen bonds.

One of the advantages of SiSiB® PC9210 over other hexa methyl di silazaneis that no base is needed as a hydrochloric acid acceptor. SiSiB® PC9210 produces ammonia which escapes easily from the reaction mixture during silylation.

For the price of HMDS/HMDZ chemical and other relevant information, please feel free to contact us.

Technical Data

CAS No.

999 97 3

EINECS No.

213-668-5

Formula

C6H19NSi2

Molecular Weight

Boiling Point

125°C

Flash Point

15°C

Ignition point

325°C

Color and Appearance

Clear colorless liquid

Density25/25°C

Refractive Index

Application

SiSiB® PC9210 hmds hexamethyldisilazanesilylating agent can be used to introduce trimethylsilyl group into organic molecules containing an active hydrogen atom such as alcohols, carboxylic acids, amines etc. The most common industrial SiSiB® PC9210 hexamethyldisilazane applicationsis in production of semi synthetic beta lactum antibiotics as ampicillin and cephalexin.

The usual procedure is to protect the carboxylic group in the antibiotic with HDMS followed by acylation with the desired acylchloride. Finally, desilylation under mild aqueous conditions gives the desired product.

Packing and Storage

SiSiB® PC9210 is supplied in 150Kg steel drum.

In the unopened original container SiSiB® PC9210 has a shelf life of one year in a dry and cool place.

For more information about hexamethyldisilazane uses, please feel free to contact us!

SiSiBSILICONES,as an excellent silicone supplier, offers a wide range of custom silicone productsfor you to choose from.



Отправить запрос, связаться с поставщиком

Кому: Nanjing SiSiB Silicones Co., Ltd
Ваш E-mail:
Текст письма:


Send to other suppliers

Другие товары поставщика

SiSiB® PC5901
SiSiB® PC5901 N Octyltrimethoxysilane SiSiB® PC5901 is a monomeric medium-chain alkylfunctional silane. It is a colorless liquid and soluble in common non-p...
Alkyl Alkoxy Modified Silicones
Alkyl Alkoxy Modified Silicones SiSiB SILICONES, established in 1989, is one of the leading silicone emulsion manufacturers, focusing on the development and manufacture of silanes...
SiSiB® PC11256
SiSiB® PC11256 Acrylates/Tris(Trimethylsiloxy)Silylpropyl Methacrylate Copolymer (and) Cyclomethicone SiSiB® PC11256 is a mixture of high molecular weight ac...
SiSiB® FS2110 Hydrophobic Fumed Silica
SiSiB® FS2110 Hydrophobic Fumed Silica Good thickening and thixotropy. Good anti-sagging properties and excellent stability in epoxy resin. Excellent reinforcing properties in sili...
Silicone Polymers & Additives
Silicone Polymers & Additives Since our establishment as a silicone softenersmanufacturer in 1989, silicone has been our core business, especially custom food and medical grade ...
Все товары поставщика

Похожие товары

SiSiB® PC9210
SiSiB® PC9210 Продавец: Nanjing SiSiB Silicones Co., Ltd Hexamethyldisilazane SiSiB® PC9210 (also called as Bis trimethylsilyl amine; HMDS chemical; ...
Endoscopic Retriever Bag
Endoscopic Retriever Bag Продавец: Victor Medical Instruments Co., Ltd. Usage of Endoscopic Retriever Bag Instruction for Use The single use endopouch retrieval bagi...
Shank Adapter HC
Shank Adapter HC Продавец: Litian Heavy Industry Machinery Co., Ltd Litian shank adapters use high-quality alloy structural steel, and adopt a complete set of mature...
Smart 32 Nucleic Acid Extraction Instrument
Smart 32 Nucleic Acid Extraction Instrument Продавец: Daan Gene Co., Ltd. Smart 32 is a nucleic acid extraction instrumentadopting magnetic bead technology. Combined with ...
Neisseria gonorrhoeae Fluorescent Polymerase Chain Reaction Diagnostic Kit
Neisseria gonorrhoeae Fluorescent Polymerase Chain Reaction Diagnostic Kit Продавец: Daan Gene Co., Ltd. Gonorrhoeae, caused by Neisseria gonorrhoeae, is the second most common bacterial STI and results...