.

Tamoxifen

Tamoxifen

Synonyms:(z)-2-(4-(1,2-diphenyl-1-butenyl)phenoxy)phenoxy)-n,n-dimethylethanamine;(z)-2-(para-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethylamine;1-para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene;1-p-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene;n-dimethyl-2-(p-(1,2-diphenyl-1-butenyl)phenoxy)-(z)-ethylamin;Nolvadex-D

CAS:10540-29-1

MF:C26H29NO

MW:371.51

EINECS:234-118-0

Tamoxifen Chemical Properties

Chemical PropertiesWhite Crystalline Solid

Melting point 97-98 °C(lit.)

Water Solubility Insoluble in water. Soluble in methanol, ethanol, propanol or propylene glycol.Soluble in dimethyl sulfoxide, dichloromethane and ethanol. Insoluble in water.

Uses:Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells. Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response mo difiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.



Отправить запрос, связаться с поставщиком

Кому: Zhuhai Wumei Technology
Ваш E-mail:
Текст письма:


Send to other suppliers

Другие товары поставщика

Avanafil
Avanafil Product Name:Avanafil Synonyms:(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidi...
Exemestane
Exemestane Product Name:Exemestane Synonyms:Aromasin;6-methylenandrosta-1,4-diene-3,17-dione;6-methyleneandrosta-1,4-diene-3,17-dione;10,13-dimethyl-6-methyl...
Amino Tadalafil
Amino Tadalafil Product Name:Amino Tadalafil Synonyms:(6R,12aR)-2-Amino-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,...
Oxandrolone (Anavar)
Oxandrolone (Anavar) Product Name:Oxandrolone (Anavar) Synonyms:17beta-Hydroxy-17-Methyl-2-Oxa-5alpha-Androstan-3-One;5-Alpha-Androstan-2-Oxa-17-Alpha-Methyl-17 Beta-O...
Testosterone Cypionate
Testosterone Cypionate Product Name:Testosterone Cypionate Synonyms:Testosterone Cyclopentane Propionate;Testosterone Cyclopentylpropionate; Testosterone 17beta-Cyclope...
Все товары поставщика

Похожие товары

Nylon 6 DTY
Nylon 6 DTY Продавец: Highsun Synthetic Fiber Technologies Co., Ltd Highsun is a professional manufacturer of textile yarn, recycled nylon 6and recycled nylon yarn....
Nylon 6 Dope Dyed
Nylon 6 Dope Dyed Продавец: Highsun Synthetic Fiber Technologies Co., Ltd Colorant mixes well with the melt through dope dyed technology in the production process to form...
Nylon 6 Cool Yarn
Nylon 6 Cool Yarn Продавец: Highsun Synthetic Fiber Technologies Co., Ltd As a textile fibersupplier, Highsun nylon-6 cool yarncontains natural materials with high therm...
Nylon 6 Chip
Nylon 6 Chip Продавец: Highsun Synthetic Fiber Technologies Co., Ltd Highsun is reputed as a manufacturer of textile filament, nylon filament, pa filamentand nylon 6...
Nylon 6 Anti-bacterial
Nylon 6 Anti-bacterial Продавец: Highsun Synthetic Fiber Technologies Co., Ltd As a manufacturer of synthetic chemical fiber, nylon yarnand nylon filament yarn, Highsun produc...