Tamoxifen
Tamoxifen
Synonyms:(z)-2-(4-(1,2-diphenyl-1-butenyl)phenoxy)phenoxy)-n,n-dimethylethanamine;(z)-2-(para-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethylamine;1-para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene;1-p-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene;n-dimethyl-2-(p-(1,2-diphenyl-1-butenyl)phenoxy)-(z)-ethylamin;Nolvadex-D
CAS:10540-29-1
MF:C26H29NO
MW:371.51
EINECS:234-118-0
Tamoxifen Chemical Properties
Chemical PropertiesWhite Crystalline Solid
Melting point 97-98 °C(lit.)
Water Solubility Insoluble in water. Soluble in methanol, ethanol, propanol or propylene glycol.Soluble in dimethyl sulfoxide, dichloromethane and ethanol. Insoluble in water.
Uses:Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells. Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response mo difiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Отправить запрос, связаться с поставщиком
Другие товары поставщика
 |
Methandienone (Dianabol) | Product Name:Metandienone(Dianabol) Synonyms:1,2-Dehydro-17-methyltestosterone;17-alpha-methyl-17-beta-hydroxy-1,4-androstadien-3-one;17alpha-meth... |
 |
Trenbolone Base | Product Name:Trenbolone Base Synonyms:beta-trenbolone;17beta-hydroxyestra-4,9,11-trien-3-one;17-hydroxyestra-4,9,11-trien-3-one;4,9,11-estratrien-... |
 |
Trenbolone Acetate | Product Name:Trenbolone Acetate Synonyms:Revalor-H;17-(acetyloxy)-(17-beta)-estra-11-trien-3-one;17-beta-acetoxy-delta-4,9,11-estratrien-3-one;17-... |
 |
17-Methyltestosterone | Product Name:17-Methyltestosterone Synonyms:Metandren;Mesterone;Methyltestosterone;4-Androsten-17alpha-Methyl-17beta-Ol-3-One;17alpha-Methyltestos... |
 |
Methenolone Acetate | Product Name:Methenolone Acetate Synonyms:17-(acetyloxy)-1-methyl-,(5-alpha,17-beta)-androst-1-en-3-on;17-beta-hydroxy-1-methyl-5-alpha-androst-1-... |
Похожие товары
 |
OSi HIOSil BDAC CAS 13170-23-5 | Продавец: OSi Holding Limited | Product Description Chemical Name: Di-tert-butoxydicaetoxysilane CAS No.: 13170-23-5 Typical... |
 |
Silicone defoamer, Fatty alcohol defoamer, Polyether defoamer, Mineral oil defoamer | Продавец: ISO certification Food Safety Production License of Anti-foaming agent Halal Certification | Our INVINO antifoams are versatile, catering to a wide range of industries including papermaking,... |
 |
Silicone defoamer, Fatty alcohol defoamer, Polyether defoamer, Mineral oil defoamer | Продавец: ISO certification Food Safety Production License of Anti-foaming agent Halal Certification | Our INVINO antifoams are versatile, catering to a wide range of industries including papermaking,... |
 |
порошок ГПМЦ | Продавец: Йида ГПМЦ | Гидроксипропилметилцеллюлоза (ГПМЦ) производится из очищенного хлопка после измельчения, затем ре... |
 |
UHMWPE Plant | Продавец: Hubei Sanli Fengxiang Technology Co., Ltd | Ultra high molecular weight polyethylene (hereinafter called as UHMWPE) is a linear structural po... |
