Tamoxifen
Tamoxifen
Synonyms:(z)-2-(4-(1,2-diphenyl-1-butenyl)phenoxy)phenoxy)-n,n-dimethylethanamine;(z)-2-(para-(1,2-diphenyl-1-butenyl)phenoxy)-n,n-dimethylamine;1-para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene;1-p-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene;n-dimethyl-2-(p-(1,2-diphenyl-1-butenyl)phenoxy)-(z)-ethylamin;Nolvadex-D
CAS:10540-29-1
MF:C26H29NO
MW:371.51
EINECS:234-118-0
Tamoxifen Chemical Properties
Chemical PropertiesWhite Crystalline Solid
Melting point 97-98 °C(lit.)
Water Solubility Insoluble in water. Soluble in methanol, ethanol, propanol or propylene glycol.Soluble in dimethyl sulfoxide, dichloromethane and ethanol. Insoluble in water.
Uses:Tamoxifen is a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor. Tamoxifen is a prodrug that is metabolized to active metabolites 4-hydroxytamoxifen (4-OHT) and endoxifen by cytochrome P450 isoforms CYP2D6 and CYP3A4. In breast cancer, the gene repressor activity of tamoxifen against ERBB2 is dependent upon PAX2. Blocks estradiol-stimulated VEGF production in breast tumor cells. Protein kinase C inhibitor. Induces apoptosis in human malignant glioma cell lines. Tamoxifen and its metabolite 4-hydroxytamoxifen are selective estrogen response mo difiers (SERMs) that act as estrogen antagonists in mammary gland. Blocks estradiol-stimulated VEGF production in breast tumor cells.
Send product request
Other supplier products
 |
Avanafil inhibito | Product Name:Avanafil Synonyms:(S)-2-(2-Hydroxymethyl-1-pyrrolidinyl)-4-(3-chloro-4-methoxybenzylamino)-5-[(2-pyrimidinylmethyl)carbamoyl]pyrimidi... |
 |
Testosterone Undecanoate (Andriol) | Product Name:Testosterone Undecanoate (Andriol) Synonyms:Testosterone Undecanoate;Testosterone Undecanoilate; 17-Beta-Hydroxy-5-Alpha-Androstan-3... |
 |
Boldenone Cypionate | Product Name:Boldenone Cypionate Synonyms:17β-Hydroxyandrosta-1,4-Dien-3-One Cyclopentanepropionate; 17beta-Hydroxy-Androsta-1,4-Dien-3-One ... |
 |
Testosterone Acetate | Product Name:Testosterone Acetate Synonyms:17-[(1-Oxoacetyl)oxy]androst-4-en-3-one;17-beta-(acetyloxy)androst-4-en-3-one;17beta-Acetoxy-DELTA4-and... |
 |
Nandrolone Propionate | Product Name:Nandrolone Propionate Synonyms:Nandrolone 17-Propionate;4-Estren-17-Beta-Ol-3-One Propionate; 4-Estren-17beta-Ol-3-One 17-Propionate... |
Same products
 |
Chemical Products for Industrial Applications | Seller: Huanuo Electric Co., Ltd. | Our chemical products are developed for a wide range of industrial applications, including manufa... |
 |
NPK 13-5-40+TE Water-soluble Fertilizer | Seller: Hebei Lvwang Ecological Fertilizer Co., Ltd. | NPK 13-5-40+TE Water-soluble Fertilizer for Vegetables and Fruits NPK 13-5-40+TE water-soluble f... |
 |
China Fertilizer Factory NPK 12-24-12 Compound Fertilizer for Rice | Seller: Hebei Lvwang Ecological Fertilizer Co., Ltd. | China Fertilizer Factory NPK 12-24-12 Compound Fertilizer for Rice NPK 12-24-12 compound Fertili... |
 |
2-Amino-6-chloropurine 10310-21-1 | Seller: Xinxiang Ruicheng Technology Co.,Ltd. | 2-Amino-6-chloropurine 10310-21-1 2-Amino-6-chloropurineis a reactive purine compound used as a ... |
 |
Xanthine 69-89-6 | Seller: Xinxiang Ruicheng Technology Co.,Ltd. | Xanthine 69-89-6 Xanthineis a natural purine base that serves as a key intermediate in purine me... |
