SR9011

Product Name: SR9011
Cas No.:
Synonyms: 3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)-N-pentylpyrrolidine-1-carboxamide
Formula: C23H31ClN4O3S
Molucelar weight: 479.03524
Packing:foil bag or as required
Chemical Name: 3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)-N-pentylpyrrolidine-
1-carboxamide
SR9011 Description and Applications:
SR9011 is atrifunctional methacrylate monomer that provides exceptional adhesion to metal substrates.
SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols.
Usage levels of 5% to 10% by weight are recommended.

Description:

SR9011 is atrifunctional methacrylate monomer that provides exceptional adhesion to metal substrates. SR9011 is recommended for use in peroxide cured coatings, sealants, and PVC-based plastisols. Usage levels of 5% to 10% by weight are recommended.SR9011 is apotent and specific synthetic REV-ERB agonist that binds to REV-ERB- with an EC50 ~790 nM and REV-ERB-with EC50 ~560 nM.

It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB- and REV-ERB- play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism. Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure.

Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic diseases.

Product Usage:
SR9011 alters the metabolic profile of skeletal muscle in amanner similar to the changes observed in animals that are endurance trained. Basically, the drug sends asignal to the muscle to tell it to modify its metabolism. Half of the mice studied showed improved running endurance in terms of both time and distance. What was clearly interesting was that asmall, drug-like molecule could increase metabolic rate in skeletal muscle and increase exercise endurance SR9011 Not Just a"Diet" Pill.

There's no way to sugarcoat it-though many have tried-maintaining ahealthy weight can be difficult. Because it's hard, many have tried "miracle" weight-loss pills and other quick fixes for something that ultimately requires alifestyle change. Many over-the-counter diet and weigh-loss pills are unregulated and may contain dangerous ingredients. SR9011, however, isn't like appetite suppressants, laxatives, or "fat blockers." And you won't find SR9011 in the ingredient lists of protein powders or exercise supplements.

The difference between SR9009 and other diet pills is in its chemistry.SR9011 is not an appetitesuppressant-as many weight-loss drugs are-and directly works by increasing the metabolic rate of muscle. Your metabolism speeds up and slows down naturally during the day, meaning that sometimes food is used for energy and sometimes it's stored as fat. By re-synching adysfunctional metabolic clock, SR9011 ensures that food and excess fat are used as energy.

SR9011 is one of apair of compounds developed at TSRI by Burris and his team. The drug binds to Rev-erb,a natural protein in the body that influences lipid and glucose metabolism in the liver, inflammatory responses, and fat-storing cells. By binding to Rev-erb, SR9011 can kickstart metabolism with another pleasant side-effect: increased muscle strength.

Related Products

Другие товары поставщика

	Drostanolone Propionate (Dromostanolone propionate, Masteron P, dros prop)	Drostanolone Propionate (Dromostanolone propionate, Masteron P, dros prop)CAS No.: 521-12-0Molecular formula: C23H36O3Molecular weight: 360.53EINE...
	SR9011	Product Name: SR9011Cas No.: Synonyms: 3-(((4-chlorobenzyl)((5-nitrothiophen-2-yl)methyl)amino)methyl)-N-pentylpyrrolidine-1-carboxamideFormula: C2...
	GW501516	Basic Information:CAS No.: Other Name: GSK-516,EndurobolM.W.: 453.50M.F.: C21H20F3NO3S2Melting Point: 173-179ºCBoiling Point: 584.543ºC a...
	Sermorelin	Sermorelin Acetate / Sermorelin (2mg/vial) to Gain Weight 86168-78-7 CAS 86168-78-7 SYNONYMS Sermorelin/ Sermorelin Acetate SEQUENCE H-Tyr-Ala-Asp-...
	GHRP-6 10mg	Ghrp-6 CAS: 87616-84-0Ghrp-6 M.F.: C46H56N12O6Ghrp-6 M.W.: 873.01Ghrp-6 Purity (HPLC): 98.0%min.Ghrp-6 Appearance: White powderGhrp-6 Single Impuri...

Похожие товары

	The Ultimate Guide to Fluorescent Dye	Продавец: Axispharm	The Ultimate Guide to Fluorescent Dye Fluorescent dyes, also known as fluorophores, are compound...
	KLUBER LECTRIC KR 44-102 1KG Grease	Продавец: Guangdong Juguangheng Automation Equipment Co.,Ltd.	NSK LR380G/PC 20PC,50PC/Carton NSK AS280G/PC 20PC,50PC/Carton NSK LG280G/PC 20PC,50PC/Carton N...
	KLUBER ISOFLEX TOPAS NCA52 75G Grease	Продавец: Guangdong Juguangheng Automation Equipment Co.,Ltd.	“LUBE FS-2-7 700G” LUBE FS-2-4 400G LUBE FS-2-2 200G LUBE FS-1-7 700G LUBE MY-2-7...
	mbbr media	Продавец: Hangzhou NIHAO Environmental Tech Co., Ltd	As a professional OEM factory and exporter of MBBR carriers, NIHAO MBBR carriers to many large en...
	Kluber ISOFLEX TOPAS L 32CN 1KG Grease for Pick and Place Machine	Продавец: Guangdong Juguangheng Automation Equipment Co.,Ltd.	NSK LR380G/PC 20PC,50PC/Carton NSK AS280G/PC 20PC,50PC/Carton NSK LG280G/PC 20PC,50PC/Carton N...