Phospho-L-Tyrosine Disodium Salt
Synthesis and Quality Control of Phospho-L-Tyrosine Disodium Salt Synthesis Routes: Chemical synthesis: Phosphorylation of L-tyrosine using phosphorus oxychloride (POCl₃) or di-tert-butyl phosphate, followed by deprotection and neutralization with sodium hydroxide. Enzymatic synthesis: Catalyzed phosphorylation of L-tyrosine by tyrosine kinases (e.g., TK) in vitro, offering higher stereoselectivity. Quality Standards: High-purity grades (≥98% HPLC) are required for research and pharmaceutical use, with strict control of impurities such as L-tyrosine, inorganic phosphate, and heavy metals (e.g., Pb <10 ppm).
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