Phenacetin Pharmaceutical Intermediates BP Grade Antipyretic Analgesic CAS:62-44-2

• 

Phenacetin Pharmaceutical Intermediates BP Grade Antipyretic Analgesic CAS:62-44-2


1. Quick Detail:

Phenacetin
CAS: 62-44-2
EINECS Number: 200-533-0
Formula: C10H13NO2
MW: 179.2157
Density: 1.099g / cm3
Melting point: 133-138 ℃
Boiling point: 355.1 ° C at 760 mmHg
Flash Point: 168.5 ° C
Water-soluble: 0.076 g / 100 mL
Vapor Pressure: 3.21E-05mmHg at 25 ° C
Uses: Anti-inflammatory drugs
Assay: 99%
Appearance: White or almost white crystalline powder


2. Descriptions:

Phenacetin is a pain-relieving and fever-reducing drug, widely used from its introduction in 1887 until banned in the US by the FDA in 1983. Its use has declined because of its adverse effects, which include increased risk of certain cancers and kidney damage. It is metabolized into paracetamol, which replaced it in some over-the-counter medications following the ban on phenacetin.


3. Applications:

Phenacetin was widely used until the third quarter of the twentieth century, often in the form of an "A.P.C." or aspirin-phenacetin-caffeine compound analgesic, as a remedy for fever and pain. An early formulation (1919) was Vincent's APC in Australia. However the U.S. Food and Drug Administration ordered the withdrawal of drugs containing phenacetin in November 1983, owing to its carcinogenic and kidney-damaging properties (Federal Register of October 5, 1983 (48 FR 45466)).

It was also banned in India.As a result some branded, previously phenacetin-based preparations continued to be sold, but with the phenacetin replaced by safer alternatives. A popular brand of phenacetin was Roche's Saridon, which was reformulated in 1983 to contain propyphenazone, paracetamol and caffeine. Coricidin was also reformulated without phenacetin. Paracetamol is a metabolite of phenacetin with similar analgesic and antipyretic effects, but the new formulation has not been found to have phenacetin's carcinogenicity.

Phenacetin is now being used as a cutting agent to adulterate cocaine in the UK and Canada, owing to the similar physical features of the two drugs.Due to low cost phenacetin is used for research into the physical and refractive properties of crystals. It is an ideal compound for this type of research.

Другие товары поставщика

	Steroid Medical Tools Solution 99.5% High Purity Test Blend 450 mg / ml For Muscle Building	Steroid Medical Tools Solution 99.5% High Purity Test Blend 450 mg / ml For Muscle Building Basic Info: Test Blend 500 each 1ml contains: 200 m...
	Anabolic Androgenic Steroid Hormone Trestolone Acetate/ Ment for Male Contraception	Anabolic Androgenic Steroid Hormone Trestolone Acetate/ Ment for Male Contraception Basic Info. Trestolone acetate CAS No.: 6157-87-5 Molecular...
	Injectable Steroid Yellow Oils Andropen 275 Mg/Ml Muscle Building Supplements	Injectable Steroid Yellow Oils Andropen 275 Mg/Ml Muscle Building Supplements Basic Info. Andropen 275mg per ml Andropen 275 is an androgenic/a...
	Cosmetic Raw Material and Whitening Arbutin 497-76-7	Cosmetic Raw Material and Whitening Arbutin 497-76-7 Basic info: Arbutin CAS: 497-76-7 MF: C12H16O7 MW: 272.25 Appearance: white powder Purity: ...
	Safe Human Growth Hormone Peptide PT - 141 Bremelanotide For Peptide Drum	Safe Human Growth Hormone Peptide PT - 141 Bremelanotide For Peptide Drum Basic Info. Product Name: PT-141 CAS: 32780-32-8 MF: C50H69N15O10 MW:...

Похожие товары

	внутривенная игла	Продавец: Shanghai Hongbiao Equipment Co.,Ltd	Intravenous indwelling needle, central venous catheter kit, endotracheal tube kit, sterile applic...
	Ultra-galvo Scanner	Продавец: Shenzhen Han\'s Scanner S&T Co., Ltd.	Ultra-galvo Scanner The xy galvanometerscanner laser using photoelectric sensor as feedback syst...
	Smart Laser Scanner	Продавец: Shenzhen Han\'s Scanner S&T Co., Ltd.	Smart Laser Scanner Hashu serie is a highly integrated galvanometer scanning system. The galvano...
	Scanning Solutions	Продавец: Shenzhen Han\'s Scanner S&T Co., Ltd.	Scanning Solutions Our scanner systems can process non-metallic and partial metallic materials. ...
	Scan Heads	Продавец: Shenzhen Han\'s Scanner S&T Co., Ltd.	Scan Heads UltraScan products cover a comprehensive range of models, suitable for customers with ...