Thyroid Peroxidase (TPO)

• 

Thy peroxidase(TPO), also called thyroperoxidase or thyroid peroxidase igg, catalyzes the iodization of thyroglobulin tyrosine during the biosynthesis of T3 and T4.

TPO is an enzyme expressed mainly in the thyroid, where it is secret into the colloid.

The increased TPO level may reflect the promoted thyroid hormone synthesis, which may cause hyperthyroidism.

The detection of TPO helps with diagnosing Hashimoto's disease (HD) and autoimmune hyperthyroidism; Toxic chronic goiter (Graves); Monitoring the effect of immunotherapy; To detect the possibility of familial thyroid disease; Prediction of postpartum thyroid dysfunction in pregnant women.

SEKBIO provides Humanised anti-human TPO mAb for diagnosis usage.

Types Of Thyroid Peroxidase (TPO)

Thyroid Peroxidase Intro

Thyroid peroxidase(TPO) TPO is an important enzyme that catalyzes thyroid hormones. TPO is synthesized by thyroid follicular cells. It is a 10% glycated hemoglobin-like protein composed of 933 amino acid residues with a molecular weight of 103 kD. It is most abundantly distributed in the microvilli on the follicular lumen surface. TPO uses hydrogen peroxide as an oxidant. TSH regulates the generation and activity of TPO. In the experiment, the action of TPO disappeared 48 hours after removing the rat pituitary, and TPO activity will restore after the injection of thyroid-stimulating hormone. Thiourea drugs can inhibit the activity of TPO, thus inhibiting the synthesis of thyroid hormones, and are commonly used clinically for the treatment of hyperthyroidism (hyperthyroidism).

Thyroid Peroxidase Antibody

Thyroid peroxidase (TPO) is a membrane-bound heme protein with a molecular weight of about 100,000. TPO participates in two different reactions in the biosynthesis of thyroid hormones. If thyroid peroxidase antibodies are present, it is a sign of concomitant damage to thyroid function or potential harm. Peroxidase antibody-positive suggests that the thyroid disease may be Hashimoto's thyroiditis.

Sekbioprovide thyroid antibodies tpo and tg, high tpo and tg antibodies, ivd antibodyand etc. want to anti thyroid peroxidase antibody test costor more, contact us.

Другие товары поставщика

	Inflammatory Marker	Inflammatory cytokines refer to various cytokines involved in the inflammatory response. And the inflammatory markers can identify the severity and...
	Recombinant COVID-19 Spike 1 His Full Length Protein	Catalog #: HP811-16 Description: Recombinant Protein, research use only Molecular weight: 29KD, theoretically Want to more about ivd raw mater...
	Tumor Marker	Tumor Marker Ca tumour markeris a chemical substance that reflects the presence of a Tumor. It is present in malignant tumour cells, not in normal...
	25-OH Vitamin D	25OH Vitamin D Vitamin D is converted to 25-hydroxyvitamin D (25OHD) by hydroxylation in the liver and the active 1, 25-dihydroxy vitamin D in the...
	Thyroid Peroxidase (TPO)	Thy peroxidase(TPO), also called thyroperoxidase or thyroid peroxidase igg, catalyzes the iodization of thyroglobulin tyrosine during the biosynthe...

Похожие товары

	PCR Tube Strips Supplier	Продавец: Zhejiang Songhai Medical Device Co., Ltd.	The most common application of PCR tubes includes various molecular biology biochemistry experime...
	Biopharmaceutical Equipment and Devices	Продавец: Jiangsu Hanbon Science&Technology Co., LTD	Hanbon is a manufacturer of liquid ssmb chromatographyseries products with a large production sca...
	SFC-Dynamic Axial Compression Column	Продавец: Jiangsu Hanbon Science&Technology Co., LTD	SFC-Dynamic Axial Compression Column (DAC) has the most mature loading technology in the field of...
	Preparative Liquid Chromatography System	Продавец: Jiangsu Hanbon Science&Technology Co., LTD	Hanbon preparative liquid chromatography system has the characteristics of high efficiency, high ...
	Preparative HPLC	Продавец: Jiangsu Hanbon Science&Technology Co., LTD	Hanbon offers Hanbon preparative HPLCand MPLC from laboratory to industrial level, which are esse...