Thyroid Peroxidase (TPO)

• 

Thy peroxidase(TPO), also called thyroperoxidase or thyroid peroxidase igg, catalyzes the iodization of thyroglobulin tyrosine during the biosynthesis of T3 and T4.

TPO is an enzyme expressed mainly in the thyroid, where it is secret into the colloid.

The increased TPO level may reflect the promoted thyroid hormone synthesis, which may cause hyperthyroidism.

The detection of TPO helps with diagnosing Hashimoto's disease (HD) and autoimmune hyperthyroidism; Toxic chronic goiter (Graves); Monitoring the effect of immunotherapy; To detect the possibility of familial thyroid disease; Prediction of postpartum thyroid dysfunction in pregnant women.

SEKBIO provides Humanised anti-human TPO mAb for diagnosis usage.

Types Of Thyroid Peroxidase (TPO)

Thyroid Peroxidase Intro

Thyroid peroxidase(TPO) TPO is an important enzyme that catalyzes thyroid hormones. TPO is synthesized by thyroid follicular cells. It is a 10% glycated hemoglobin-like protein composed of 933 amino acid residues with a molecular weight of 103 kD. It is most abundantly distributed in the microvilli on the follicular lumen surface. TPO uses hydrogen peroxide as an oxidant. TSH regulates the generation and activity of TPO. In the experiment, the action of TPO disappeared 48 hours after removing the rat pituitary, and TPO activity will restore after the injection of thyroid-stimulating hormone. Thiourea drugs can inhibit the activity of TPO, thus inhibiting the synthesis of thyroid hormones, and are commonly used clinically for the treatment of hyperthyroidism (hyperthyroidism).

Thyroid Peroxidase Antibody

Thyroid peroxidase (TPO) is a membrane-bound heme protein with a molecular weight of about 100,000. TPO participates in two different reactions in the biosynthesis of thyroid hormones. If thyroid peroxidase antibodies are present, it is a sign of concomitant damage to thyroid function or potential harm. Peroxidase antibody-positive suggests that the thyroid disease may be Hashimoto's thyroiditis.

Sekbioprovide thyroid antibodies tpo and tg, high tpo and tg antibodies, ivd antibodyand etc. want to anti thyroid peroxidase antibody test costor more, contact us.

Other supplier products

	Tumor Marker	A antigen markersis a chemical substance that reflects the presence of a Tumor. It is present in malignant tumour cells, not in normal adult tissue...
	Testosterone (Testo)	Testosterone (Testo) Testosteroneis the primary male sex hormone and an anabolic steroid. In male humans, male testosteroneplays a vital role in d...
	Thyroglobulin (Tg)	Thyroid thyroglobulinis a 660 kDa, a dimeric glycoprotein produced by the follicular cells of the thyroid and released into the residual cavity of ...
	Thyroid Function	Thyroid Function The thyroid gland is a 2-inches long, butterfly-shaped endocrine gland generally located in the lower front of the neck. The ...
	Creatine Kinase-MB (CKMB)	Creatine kinase isoenzymes are an enzyme component, among which MB type is mainly present in myocardial cells. It is also a kind ofcardiac marker. ...

Same products

	RF4 Series Trinocular Stereo Microscope Rocker Arm Stand	Seller: Shenzhen weikexiu technology Co.,Ltd	Description RF4 RF-FX23A RF-FX35A 7-50X continuous zoom trinocular microscope with foldi...
	Medical Polyisoprene rubber pad for soft transfusion bag	Seller: Taizhou KangLong Medical Treatment Technology Co., Ltd.	Medical Polyisoprene rubber pad for soft transfusion bag Stable production, Mature technology, Q...
	The 51-piece Emergency Survival First Aid Bag	Seller: Dongyang City Yonoel Outdoor Products Co., Ltd.	This Compact And Well-Organized First Aid Kit Is Designed To Provide A Wide Range Of Medical Supp...
	RELIFE RL-M6T Pro B11 6.5X-65X Trinocular Stereo Microscope	Seller: Phonefix	RELIFE RL-M6T Pro-B11 6.5X-65X Continuous Zoom Trinocular Stereo Microscope with B11 large area b...
	Smoke Toxicity Tester	Seller: Qinsun Instruments Co., Ltd	Code for Gaseous Toxicity Caused by Combustion of Cable Materials in NES Standard of British Nava...