Tamoxifen Citrate (Nolvadex) Powder | Raw SERMs Anti-Estrogen Drugs Drugs CAS:54965-24-1
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amoxifen Citrate Description
Tamoxifen Citrate is the trade name for the drug tamoxifen citrate, it is a non-steroidal agent that demonstrates potent anti-estrogenic properties. The drug is technically an estrogen agonist/antagonist, which competitively binds to estrogen receptors in various target tissues. With the tamoxifen molecule bound to this receptor, estrogen is blocked from exerting any action, and an anti-estrogenic effect is achieved.
Tamoxifen Citrate is an estrogen agonist in the liver, capable of activating the estrogen receptor and mimicking the actions of this sex hormone in this region of the body. As such it can have a markedly positive impact on HDL (good) cholesterol values, as does estrogen.
Tamoxifen Citrate Application
1. Breast cancer
Tamoxifen Citrate is currently used for the treatment of both early and advanced estrogen receptor (ER)-positive (ER+) breast cancer in pre- and post-menopausal women.[10] Additionally, it is the most common hormone treatment for male breast cancer.
2. Infertility
Tamoxifen Citrate is used to treat infertility in women with anovulatory disorders. It is given at days 3-7 of a woman’s cycle.
3. Gynecomastia
Tamoxifen Citrate is used to prevent estrogen-related gynecomastia, resulting from elevated estrogenic levels. It is taken as a preventative measure in small doses, or used at the onset of any symptoms such as nipple soreness or sensitivity.
4. Others
Occasionally Tamoxifen Citrate is used in treatment of the rare conditions of retroperitoneal fibrosis and idiopathic sclerosing mesenteritis.
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