KALIOTOXIN

The potent blocker of voltage-sensitive K+ channels (IC50 values are 0.1, 1.1, and 25 nM for KV1.3, KV1.1, and KV1.2 channels) respectively). Also inhibits Ca2+-activated K+ channels.

SPECIFICATION OF KALIOTOXIN

CAT	K1070-V
CAS NO.
Product Name	Kaliotoxin
Purity	> 98%
Form/State	Lyophilized powder
Solubility	Soluble in water
Molecular weight
Molecular formula	C171H283N55O49S6
Source	Synthetic peptide
Storage	Shipped at room temperature. The product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20C.
Storage of solutions	Up to two weeks at 4C or three months at -20C.
Sequence	GVEINVKCSGSPQCLKPCKDAGMRFGKCMNRKCHCTPK (Disulfide bonds between Cys8-Cys28, Cys14-Cys33 and Cys18-Cys35)

APPLICATION OF KALIOTOXIN

Kaliotoxin (KTX), a specific blocker of potassium channels, exerts various toxic effects due to its action on the central nervous system.

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